DRSC/TRiP Functional Genomics Resources

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Protein Alignment jumu and Foxg1

DIOPT Version :10

Sequence 1:NP_524302.1 Gene:jumu / 41265 FlyBaseID:FBgn0015396 Length:719 Species:Drosophila melanogaster
Sequence 2:NP_032267.1 Gene:Foxg1 / 15228 MGIID:1347464 Length:481 Species:Mus musculus


Alignment Length:191 Identity:54/191 - (28%)
Similarity:87/191 - (45%) Gaps:40/191 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   357 GSPSSLSSSSASSPLGNVSNLVNIANNNTSGAGSGLVKPLQQKVKLPPVG-------------SP 408
            |.|:.|      :|:|        .:....|||:|    .::|......|             ..
Mouse   124 GGPAEL------APVG--------PDEKEKGAGAG----GEEKKGAGEGGKDGEGGKEGDKKNGK 170

  Fly   409 FPKPAYSYSCLIALALKNSRAGSLPVSEIYSFLCQHFPYFENAPSGWKNSVRHNLSLNKCFEKIE 473
            :.||.:||:.||.:|::.|....|.::.||.|:.::|||:.....||:||:||||||||||.|: 
Mouse   171 YEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKV- 234

  Fly   474 RPATNGNQRKGCRWAMNPDR----INKMDEEVQKWSRKDPAAI---RGAMVYPQHLESLER 527
             |....:..||..|.::|..    |.....::::.|....|.:   |||.:....|..::|
Mouse   235 -PRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDR 294

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jumuNP_524302.1 COG5025 <254..>523 CDD:227358 52/185 (28%)
FH_FOXN1-like 411..491 CDD:410804 34/79 (43%)
Foxg1NP_032267.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 31..173 11/66 (17%)
FH_FOXG 173..251 CDD:410795 34/79 (43%)
COG5025 <176..>348 CDD:227358 41/121 (34%)
Required for interaction with TLE6. /evidence=ECO:0000269|PubMed:16314515 241..336 12/54 (22%)
Interaction with KDM5B. /evidence=ECO:0000250 375..398
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 419..447
Blue background indicates that the domain is not in the aligned region.

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