DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jumu and Foxc2

DIOPT Version :9

Sequence 1:	NP_524302.1	Gene:	jumu / 41265	FlyBaseID:	FBgn0015396	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_038547.2	Gene:	Foxc2 / 14234	MGIID:	1347481	Length:	494	Species:	Mus musculus

Alignment Length:	221	Identity:	57/221 - (25%)
Similarity:	99/221 - (44%)	Gaps:	34/221 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 MQSNYSLGSPSSL---------SSSSASSPLGNVSNLVNIANNNTSGAGSGLVKPLQQKVKLPPV 405
            ||:.||:..|::|         :...|:...|.:::.:.:.:.:....|:|:.:........|..
Mouse     1 MQARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYGAGMGRSYAPYHHQPAA 65

  Fly   406 GSPFPKPAYSYSCLIALALKNSRAGSLPVSEIYSFLCQHFPYFENAPSGWKNSVRHNLSLNKCFE 470
            .....||.|||..||.:|::|:....:.::.||.|:...||::.....||:||:|||||||:||.
Mouse    66 PKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFV 130

  Fly   471 KIERPATNGNQRKGCRWAMNPDRINKMD-----EEVQKWSRKDPAAIRGAMVYPQHLESLERGEM 530
            |:  |..:....||..|.::||..|..:     ...:::.:||         .|:..|  ||..:
Mouse   131 KV--PRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD---------VPKDKE--ERAHL 182

  Fly   531 KH-------GSADSDVELDSQSEIEE 549
            |.       |:.......|...|.|:
Mouse   183 KEPPSTTAKGAPTGTPVADGPKEAEK 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jumu	NP_524302.1	Forkhead	411..499	CDD:278670	35/92 (38%)
Foxc2	NP_038547.2	FH	71..159	CDD:214627	35/89 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	166..213		11/54 (20%)
		EBP50_C	167..>257	CDD:286142	11/53 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	233..267
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	381..422
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820