DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jumu and foxc1a

DIOPT Version :9

Sequence 1:	NP_524302.1	Gene:	jumu / 41265	FlyBaseID:	FBgn0015396	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_571803.1	Gene:	foxc1a / 100148408	ZFINID:	ZDB-GENE-010302-1	Length:	476	Species:	Danio rerio

Alignment Length:	185	Identity:	56/185 - (30%)
Similarity:	90/185 - (48%)	Gaps:	37/185 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 MQSNYSLGSPSSLSSSSASSPLGNVSNLVNIANNNTSGAG---SGLVKPL---------QQKVKL 402
            ||:.||:.||:|         ||.|..:.:..:...:.||   :|:..|:         |....:
Zfish     1 MQARYSVSSPNS---------LGVVPYISSDQSYYRAAAGGGYTGMPAPMTMYSHAAHDQYPASM 56

  Fly   403 -----PPVGSPFP----KPAYSYSCLIALALKNSRAGSLPVSEIYSFLCQHFPYFENAPSGWKNS 458
                 |....|.|    ||.|||..||.:|::||....:.::.||.|:.:.||::.:...||:||
Zfish    57 ARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNSPDKKVTLNGIYQFIMERFPFYRDNKQGWQNS 121

  Fly   459 VRHNLSLNKCFEKIERPATNGNQRKGCRWAMNPDRINKMD-----EEVQKWSRKD 508
            :|||||||:||.|:  |..:....||..|.::||..|..:     ...:::.:||
Zfish   122 IRHNLSLNECFVKV--PRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jumu	NP_524302.1	Forkhead	411..499	CDD:278670	36/92 (39%)
foxc1a	NP_571803.1	Forkhead	74..160	CDD:278670	36/87 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	169..271		2/6 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	284..303
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820