Protein Alignment CG12592 and LOC4577154

DIOPT Version :10

• Sequence 1: NP_731474.1
• Gene: CG12592 / 41263
• FlyBaseID: FBgn0037811
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_001237516.4
• Gene: LOC4577154 / 4577154
• VectorBaseID: AGAMI1_004672
• Length: 1803
• Species: Anopheles gambiae
• Alignment Length: 838
• Identity: 155/838 - (18%)
• Similarity: 303/838 - (36%)
• Gaps: 231/838 - (27%)

  Fly    18 ELSSSL---------SSSVASKFKEFSKRKRISDSFS-----DLSEELERIGLRQMRKRIKLEKS 68
            |:|.|:         :||||:  |..|:.:::|.|:|     ..::.::...:|:..::.:||:.
Mosquito   421 EISDSIMEANTSVKDTSSVAN--KSTSEGEKLSQSWSQSVRRSATKGIDEFSVRKQEEQERLEEE 483

  Fly    69 FERTPKKKVQTKKHLPPVRKKDSVKRRRIIIASPSDEEHDGKVQTNDDSSENKTE-KPKNQ---- 128
            .|:..|..:::     |::.:....:     |:.:||..|   :.|||..|::.| :.||:
Mosquito   484 TEKLQKAPLKS-----PLKPRSPAAK-----AASADESID---EDNDDELEDEEEAQDKNELLDD 535

  Fly   129 -----------SNCSSNASKLSEAAQLLNV--------SEEKSSISETELERSRQVALNELNKSE 174
                       .:.:|:..:..|..::::.        :||.....|.|.:.:....::..:::|
Mosquito   536 EAVEMEGYESGDSLASDLRREMEENEIMDQGEDLGSEDTEENDEQEEDEEDGNDSWIVSSGDEAE 600

  Fly   175 RFNKTETQLDISVMEVDSSDHDEEEKTEKVGAKNNRSLYEIVDSDDEEEQ--DQDQSDAAK---- 233
            :.|:.|...|....::.:.:...::| ||......|.:.|:||..||:.:  |:::.:.||
Mosquito   601 QLNEDELLKDTEDEDLQTKNSSVKDK-EKTKTPKRRRIIEMVDDSDEDTKASDEERKETAKSPRN 664

  Fly   234 -----------------PAESENHSEIKKSTSFMDQ-----MSGAKGNKSVYEIMDSYETEDPKE 276
                             |.:..|.|:|..:....||     .:.||.:.|    |:|  :.|.::
Mosquito   665 LSSKRSLTPVGGKENNTPTKKLNLSQINDAVKNKDQDKPANNTPAKNDTS----MES--STDEQQ 723

  Fly   277 AGKNE---------------------------------ESDKDKPAENGKSDKDKQAETEMSDED 308
            .|.||                                 ..:|:..||:.::|....:||...|.:
Mosquito   724 VGNNETMLPATPAHKTPSKDTGAALHSATKSLSNSKHGNGEKEVAAEDDENDTSGNSETMFQDAE 788

  Fly   309 KPSEI--KSPSTIKKSI-ISTADEEALLAE--------------LASSDLSHLEKMFNPLQKSRR 356
            ...|.  ||...::|.: :|.:..::::|.              :....|.....|...:|....
Mosquito   789 DGGETVQKSDDAMEKDVSLSKSPTKSVIASRKSFPAASITTKDVIGRKSLPANANMQAAIQSETD 853

  Fly   357 QSLHVPSPELAAKNPKLRRRS---ERVEVGN--------DFCPSQSFVDMVAEKKRQKNKRKRLS 410
            :......|: |.:|.::....   |.|||.|        :..|::..:|..|::...|..|
Mosquito   854 EGGESSQPD-ATQNDEVEEVEALVENVEVENAEHDKTQAEPAPAEFTLDQPADEAPTKPGR---- 913

  Fly   411 KSLSGAPEDLEEMEIKHERKRLKSSHGASTDSMEEDNENETMTVAEEHHSDGEVSNGEVPIEEKP 475
            ||:...|....:..|...:||...:.|       ||...:|.|........|:....:.|:|:|.
Mosquito   914 KSMPAVPLISAQFYIGASKKRATIAGG-------EDAHVQTSTPKSNQSLSGKDKGKKTPVEKKA 971

  Fly   476 TTSS-----------EKPSASELPEEGNSAPPALKKDVKRLQAARQAVSHAVNLLAPPK----AT 525
            ||::           .|..|....:.|.......|||..|.....|.|..::.:...|.    |.
Mosquito   972 TTANGGSTVLNPFAQAKNKARLSLDSGAGQQKPEKKDKLRRSLPSQFVEESMEVDEAPMNENVAE 1036

  Fly   526 EAEPRTLSRKLSPQPPVVDKKSAKQKKKGKKKQKPQEASPLKSSDEENHGHRIRTNAGYVTVVDE 590
            |.......::::.:..||:.:..:..|:..|..||:..: |:..|..|    |.:....|...|:
Mosquito  1037 EPSKPDDDKEMNDEVEVVENQEPENGKQQSKAPKPKRKA-LEDYDLAN----ILSRCNEVIREDK 1096

  Fly   591 PPTKVPIIELIKTSSGMVRVEPCTPKQKYFRELPPTPKMHGFR---------------------- 633
                    |..|..:..:|.:  ..::|..|||....::...:
Mosquito  1097 --------ERKKEVASAIRKK--KEEKKRLRELEKQEELEAAKAAAAAAAAAAGSGGTTNGDDGG 1151

  Fly   634 --------EEPGPSGMSRKRAKHAAPKVEH----------NSAKQAALRFKEQIFARR 673
                    :.....|...|:.|...|||::          ....:.|||.|.::..||
Mosquito  1152 LNSSTTGNDSLSQGGEGLKKKKKRKPKVKNYLLDELAETRKERLEQALRHKLEVIERR 1209