Protein Alignment CG12592 and Iws1

DIOPT Version :10

• Sequence 1: NP_731474.1
• Gene: CG12592 / 41263
• FlyBaseID: FBgn0037811
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001385564.1
• Gene: Iws1 / 291705
• RGDID: 1304762
• Length: 765
• Species: Rattus norvegicus
• Alignment Length: 733
• Identity: 146/733 - (19%)
• Similarity: 250/733 - (34%)
• Gaps: 195/733 - (26%)

  Fly    10 GDAAYIQDELSSSLSSSVASKFKEFSKRKRISDSFSDLSEELERIGLRQMRKRIKLEKSFERTPK 74
            |.|..:|||..|.                  ||...|::|:........:.:..:.|.|    .:
  Rat    14 GGATPVQDERDSG------------------SDGEDDVNEQHSGSDTGSVDRHSENETS----DR 56

  Fly    75 KKVQTKKHLPPVRKKDSVKRRRIIIASPSDEEHDGKVQTNDDSSENKTEKPKNQSNCSS--NASK 137
            :...||.|.....:.|....   :.||.|:.|...:.:.:|..||...|.|.:.|...:  ....
  Rat    57 EDGLTKIHNGTDSENDEPSN---VHASDSESEELHRPKDSDSESEEHAESPASDSENEAVHQQGS 118

  Fly   138 LSEAAQLLNVSEEKSSISETELERSRQVALNELNKSERFNKTETQLDISVMEVDSSD-------- 194
            .||..:|||     ...|::|.|..|:.|.::       ::||..|.....|.||.|
  Rat   119 DSEKEELLN-----GHASDSEKEEGRKHAASD-------SETEDTLQPQGSESDSEDPPRPQASD 171

  Fly   195 -HDEEEKTEKVGAKNNRSLYEIVDSDDEEE-------QDQDQSDAAKP----AESENHSEIKKST 247
             ..||....::....:..|.:...||.|.|       .|.:..:..||    :|||:....:.|.
  Rat   172 SESEEPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPRPQASD 236

  Fly   248 SFMDQMSGAKGNKSVYEIMDSYETEDPKE--AGKNEESD----KDKPAENGKSDKDKQAETEMSD 306
            |..:::...:       :.|| |:|||::  |..:|..|    |:||.......::|:.::|:.:
  Rat   237 SESEELPKPR-------VSDS-ESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQN 293

  Fly   307 E-----------DKPSEIKSPSTIKKSIISTADEE------------ALLAELASSDLSHLEKMF 348
            |           ...||.:.|.  ::.|.|..|.|            |:|::....|.:...|..
  Rat   294 ESDGHADRKGLHSSDSEEEEPK--RQKIDSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAAKKS 356

  Fly   349 NPLQKSRRQSLHVPSPELAAKNPKLRRRSERVEVGNDFCPSQSFV------DMVAEKKRQKNKRK 407
            ..:..:......|.|.:...:...:...||. |||.:    :|.|      |:........|:.:
  Rat   357 RVISDADDSDSDVVSDKSGKREKTVASDSEE-EVGKE----ESSVKKSEEKDLFGSDSESGNEEE 416

  Fly   408 RLSKSLSGAPEDLEEMEIKHERKRLKSSHGASTDSMEEDNENETMTVAEEHHSDGEVSNG----- 467
            .|...:.|...|.||.|..          |.:.:.:||:.....:..||:..||..:..|
  Rat   417 NLIADIFGESGDEEEEEFT----------GFNQEDLEEEKNETQLKEAEDSDSDDNIKRGKHMDF 471

  Fly   468 ----EVPIEEKPTTSSEK-------------------------PSASELPEEGNSAPPALKK--- 500
                |:.::.|.:...::                         .:|.|..:..|...|||||
  Rat   472 LSDFEMMLQRKKSMCGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTL 536

  Fly   501 -----------DVKRLQAARQAVSHAVNLLAPPKATEAEPRTLSR----KLSPQPPVVDKKSAKQ 550
                       |:|. ......|..|:.....|....:.|....|    |:..:.|.|.:::.|.
  Rat   537 LPTVVMHLKKQDLKE-TFIDSGVMSAIKEWLSPLPDRSLPALKIREELLKILQELPSVSQETLKH 600

  Fly   551 KKKGKK----KQKPQEASPLKSSDEENHGHRIRTNAGYVTVVDEPPTKVPIIELIKTSSGMVRVE 611
            ...|:.    .:.|:|:    .|:::..|..|.            ....||..|.....||.|.|
  Rat   601 SGIGRAVMYLYKHPKES----RSNKDMAGKLIN------------EWSRPIFGLTSNYKGMTREE 649

  Fly   612 PCTPKQKYFRELPPTPKM 629
               .:|:...::|...:|
  Rat   650 ---REQRDLEQMPQRRRM 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12592	NP_731474.1	None
Iws1	NP_001385564.1	MSCRAMM_ClfA	<18..417	CDD:468110	93/450 (21%)
		TFIIS_I	<474..738	CDD:469629	37/211 (18%)