DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12592 and Samd15

DIOPT Version :9

Sequence 1:	NP_731474.1	Gene:	CG12592 / 41263	FlyBaseID:	FBgn0037811	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_001277217.1	Gene:	Samd15 / 238333	MGIID:	2685109	Length:	620	Species:	Mus musculus

Alignment Length:	666	Identity:	134/666 - (20%)
Similarity:	235/666 - (35%)	Gaps:	185/666 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 NDDSSENKTEKPKNQSN---CSSNASKLSEAAQLL--NVSEEKSSISETELE--RSRQVALNELN 171
            |.||.|:.:.:||...:   .::||..|.|.:..|  |...:..::....||  |:|:..|..:.
Mouse     9 NSDSDESLSLQPKRTKSGKLHNANADTLFEVSSKLSPNTDRDPGNVGNVPLEPTRTRKGDLVPVG 73

  Fly   172 KSERF-----------------NKTETQLDISVMEVDSSDHDEEEKTEKVGAKNNRSLYEIVDSD 219
            |:...                 .:|.|||...:        |.|:||..:.::..|.
Mouse    74 KNHEVPDLQRQDVSVGVFKGPPTRTGTQLPTKI--------DPEQKTPDIRSEKLRK-------- 122

  Fly   220 DEEEQDQDQSDAAKPAESENHSEIKKST--------SFMDQMSGAKGNKSVYEIMDSYETEDPKE 276
            ..||:....|...|..:.:..|..:|||        .|.|:           ::..|.|..|.|.
Mouse   123 SVEEEALPPSKMTKSEKKQKESIKEKSTEPYEVTKPKFPDR-----------KLRKSTEEADLKP 176

  Fly   277 AGKN-EESDKDKPAENGKSDKDKQAETEMSD----EDKPSEIKSPSTIKKSIISTADEEALLAEL 336
            ..|: |:|..::|.:....||..:..|:...    ||...|.:.|  |.::.:..:.:..|.|..
Mouse   177 HFKSTEQSGTEQPEQTKFPDKKLRQSTKKKVSGPLEDFEEESRRP--IDEASLELSQKRPLKASK 239

  Fly   337 ASSDLSHLEK-----------MFNPLQKSRRQSL--HVPSP----ELAAKNPKLRRRSER----- 379
            .:...|..||           :.:..::::.:|:  .||.|    :.:|:..|||:.|||
Mouse   240 KAQKSSFDEKFPEMLEQITVELLDDQEETQEESIKEKVPEPLGDRKPSAQKHKLRKSSERSKLKD 304

  Fly   380 --VEVGNDFCPSQSFVDMVAEKKRQKNKRKRLSKSLSGAPEDLEEMEIKHERKRLKSSHGASTDS 442
              :|...|..|.     :..:.:..|.|..:.::.....|:.:.:.:|:.:             |
Mouse   305 TLIEPSKDKDPG-----LQTQTEFPKEKLIKTTEKTGDKPQQITDPDIQEK-------------S 351

  Fly   443 MEEDNENETMTVAEEHHSDGEVSNGEVPIEEKPTTSSEKPSASELPEEGNSAPPALKKDVKR--- 504
            ..|..|...           |:.|...|.||:.....:||.:|:..........||...:|.
Mouse   352 QPEPTEKNL-----------ELPNKPKPEEERDLPKEDKPESSKPNYPAGKDKLALPAKIKTEFI 405

  Fly   505 LQAARQAVSHAVNLLAPPKATEAEPRTLSRKLSPQPPVVDKKSAKQKKK------------GKKK 557
            :.:.|::|.....|.    .|:...:.|...::...|:||...::.:.:            |:|:
Mouse   406 VGSPRESVESFSTLY----ETQEFLKDLQTDMNELFPIVDASESQTELRDSTVLPQEVELLGRKE 466

  Fly   558 QKPQ---EASPLKSSDE-------------------EN--HGHRIRTNAGYVTVVDEPPTKVPII 598
            .||.   |...|..|.|                   ||  :|.::.    :|...:.|...:...
Mouse   467 TKPSLTPEFEHLTWSPERVAEWISDLGFPQYKECFTENFINGQKLI----HVNCSNLPQMGITDF 527

  Fly   599 ELIKTSSGMVRV-----EPCTPKQKYFRELPPTPKMHGFREEPGPSGM---SRKRAK--HAA--- 650
            |.:|..|...||     ||...:.   ..||.......|.|:.|.||:   |...||  .||
Mouse   528 EDMKAISYHTRVLLGIEEPLFSRS---ISLPYRDNKGLFFEQKGHSGVKSDSLTLAKFVEAAGLQ 589

  Fly   651 ---PKVEHNSAKQAAL 663
               |:::....|:.||
Mouse   590 EYNPEIKAEEKKEDAL 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12592	NP_731474.1	None
Samd15	NP_001277217.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..394		87/442 (20%)
		SAM_Samd14	478..544	CDD:188929	13/69 (19%)
		SAM	479..533	CDD:197735	9/57 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	594..620		3/12 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843288
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930