Protein Alignment CG12592 and SAMD15

DIOPT Version :10

• Sequence 1: NP_731474.1
• Gene: CG12592 / 41263
• FlyBaseID: FBgn0037811
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001010860.1
• Gene: SAMD15 / 161394
• HGNCID: 18631
• Length: 674
• Species: Homo sapiens
• Alignment Length: 481
• Identity: 109/481 - (22%)
• Similarity: 172/481 - (35%)
• Gaps: 109/481 - (22%)

  Fly    15 IQDELSSSLSSSVASKFKEFSKRKRISDSFSDLS--EELERIGLRQMRKRIKLEKSFERTPKKKV 77
            |..|:.|..|..:...||:.......:...|||.  ||.:    ..:.:.:.||.:.|..|..
Human   103 IHQEVKSETSREMGEFFKDLEAPMDETHKESDLEPPEEAK----PNVTEDVFLESAMETDPDP-- 161

  Fly    78 QTKKHLPPVRKKD-----SVKRRRIII----ASPSDEEHDGKVQTNDDSSENKTEKPKNQSNCSS 133
                 :||.....     :|:.|.:.:    ..|...|...:||..:...|     |..|:....
Human   162 -----VPPTETMSEVSGATVRERNLELLEEETEPGVPEESLRVQHEETGLE-----PPEQTKQDF 216

  Fly   134 NASKLSEAAQLLNVSEEKSSISETELERSR------------QVALNELNKSERFNKTETQLDIS 186
            .:.||.|:.:..::...|.:..||..|..|            |..|..|.|..|.:..|..|:
Human   217 PSEKLGESLEETDLQPPKMTKPETPEETQRESTEKKRTEPPEQARLEFLEKEPRKSSEEAGLE-- 279

  Fly   187 VMEVDSSDHDEEEKTEKVGAKNNRSLYEIVDSDDEEEQDQDQSDAAKPAESENHSEIKKSTSFMD 251
             ...::.....||...|...:....|.|....|..:.:.:..:|...|...|   |||  ..|.:
Human   280 -PPEETQPEVPEEMQRKATEEKGTELPERTKPDFPDHKPRKSTDENVPEPLE---EIK--LEFPE 338

  Fly   252 QMSGAKGNKSVYEIMDSYETEDPKEAGK-NEESDKDKPAENGK---------------------- 293
            :.|.....:::.|..:..:.|.|:|..| ||:.:...|.|.|.
Human   339 EESRKTNEETILEQSEMMKPESPEEIRKSNEKKNPQPPEETGPVLPQEINPQVEEKTQTKPTEKI 403

  Fly   294 ---SDKDKQAET--EMSDEDKPSEIKSPSTI----------KKSIISTAD----EEALLAELASS 339
               .|:.|..||  |.|.||:|..|||..::          |:..:|.:|    |...|..|..|
Human   404 LELPDETKPRETHVEFSKEDRPEPIKSKYSVGNDELEHREPKRGKLSLSDKFRKEYYALGSLRES 468

  Fly   340 DLS---HLEKMFNPLQKSRRQSLHVPSPELAAKNPKLRRRSERVEVGNDFCPSQSFVDMVAEKKR 401
            :.|   |.| ...||||    .|:| |.|.:..:|     ||.....::|...:..||:..|.|
Human   469 EESIGTHYE-FLQPLQK----LLNV-SEECSYSDP-----SESQTELSEFVHEKEVVDLSQELK- 521

  Fly   402 QKNKRKRLSKSLSGAPEDLEEMEIKH 427
                 :|:|:.....||...|::.:|
Human   522 -----ERVSEDDETQPEKGTELQFEH 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12592	NP_731474.1	None
SAMD15	NP_001010860.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..448		78/368 (21%)
		ftsN	137..>310	CDD:274041	37/191 (19%)
		PTZ00341	<238..432	CDD:173534	47/201 (23%)
		SAM_Samd14	543..609	CDD:188929	109/481 (23%)