Protein Alignment CG12592 and iws1

DIOPT Version :10

• Sequence 1: NP_731474.1
• Gene: CG12592 / 41263
• FlyBaseID: FBgn0037811
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_002664782.3
• Gene: iws1 / 100329390
• ZFINID: ZDB-GENE-120914-2
• Length: 824
• Species: Danio rerio
• Alignment Length: 781
• Identity: 166/781 - (21%)
• Similarity: 278/781 - (35%)
• Gaps: 231/781 - (29%)

  Fly    10 GDAAYIQDELSSSLSSSVASKFKEFSKRKRISD--------------------------SFSDLS 48
            |.|..:|||...:...|..|.........|.||                          |.|||.
Zfish    12 GSATPVQDEQEDAGPGSRQSDDDGSDNEDRKSDNSDSEMEPPRPADSDEDSSSPVKRRASTSDLE 76

  Fly    49 EELERIGL-------RQMRKRIKLE---KSFERTPKKKVQTKKHLPPVRKKDSVKRR-RIIIASP 102
            ||.|:...       :|.|:..|.:   .|.|..||::  |:.|.....::...|.: :..:.|.
Zfish    77 EEEEKTHAASDSEEEQQKRRSPKSDAGSDSDEDRPKQR--TQNHSEDEDEEGGRKGKWKTAMNSE 139

  Fly   103 SDEEHD-GKVQTNDDSSENKTEKPKNQSNCSSNASKLSEA--AQLLNVSEE------KSSISETE 158
            |:|:.| .|.:...|..:   ::||.:...|.:..:..|.  .::|...:|      ::..|:.|
Zfish   140 SEEDEDRAKEEAGSDEDD---KRPKRRDLGSDDDDEDDEGPKTRVLGSDDEDEGPKRRALGSDDE 201

  Fly   159 LERSRQVAL------NELNKSERFNKTETQLDISVMEVDSSDHDEEEKTEKVGAKNNRSLYEIVD 217
            .||.::.||      :|..|.:..|..|.........:||.|.||::|..|..|         :|
Zfish   202 DERPKRKALGSDDDEDEEPKQKALNSDEDDKRPKRKALDSDDDDEDDKRPKRKA---------LD 257

  Fly   218 SDDEEEQDQDQSDAAKPAESENHSEIKKSTSFMDQMSGAKGNKSV-------------------- 262
            |||::::|:.....|..::.:.....|:.....|...|...:|::
Zfish   258 SDDDDDKDEGPKRKALGSDDDEDEGPKRKALGSDDDDGGPKSKALDSDDDEDERPKRKVLASDDE 322

  Fly   263 -----YEIMDSYETEDPKEAGKNEESDKDKP-----AENGKSDKDKQAETEMSDEDKPSEIKSPS 317
                 .:.:||.|.|.||....:.:.:.::|     |.:.:.|:..:.:...||:|:..:.| |.
Zfish   323 DEGPKRKALDSDEDEGPKRKALDSDDEDERPKRRALASDDEDDEGPKRKALGSDDDEDEDDK-PV 386

  Fly   318 TIKKSIISTADEEALLAELASSDLSHLEKMFNPLQKSR----------RQSLHVPSPELAAKNPK 372
            ..||:::|.:||:.             ||   .::|||          .:....|...|||   |
Zfish   387 KRKKAVLSDSDEDE-------------EK---AVKKSRIVSDDDDSGSDEGSGGPDKSLAA---K 432

  Fly   373 LRRRSERVEVGNDFCPSQSFVDMVAEKKRQKNKRKRLSKSLSGAPEDLEEMEIKHERKRLKSSHG 437
            |:      |:|:|   |:...||   ||.:..|:.  .|:|.|:..|....|   |.|.:....|
Zfish   433 LK------ELGSD---SEDEEDM---KKGEAGKKD--EKALFGSDSDSGGDE---EEKMIADIFG 480

  Fly   438 ASTDSMEED----NENETMTVAEEHHSDGEVSNGEVPIEEKPTTSSEKPSASELPEEGNSAPPAL 498
            .|.|..||:    |:.|.           |....:..:..:.....:..|...:...|.......
Zfish   481 ESGDEEEEEFTGFNQEEL-----------EAERPQTQVSGQRKADDDSDSDDGIDRGGKDMSYMS 534

  Fly   499 KKDV----KRLQAARQA--------VSHAVNLLAP--PKATEA--EPRTLSRKLSPQPPVVDKKS 547
            ..|:    |:.|:.::.        :|.|.::::.  .|.|||  |.|||:
Zfish   535 DFDMMLARKKAQSGKRRRNRDGGTFISDADDVVSAMITKMTEAAEEDRTLN-------------- 585

  Fly   548 AKQKKKGKKKQK--PQEASPLKSSD-EENHGHRIRTNAGYVTVVDE-----PPTKVPIIELIKTS 604
             .|||...||..  |.....||..| :|..     .::|.:..:.|     |...:|.:.
Zfish   586 -SQKKPALKKLMLLPTVVMHLKKQDLKETF-----IDSGVMAAIKEWISPLPDKSLPALR----- 639

  Fly   605 SGMVRVEPCTPKQKYFRELPPTPKMHGFREEPGPSGMSR------KRAKHAAPKVEHNSAKQAAL 663
               :|.|    ..|..:|||...     :|....||:.|      |..|.:.|.      |..||
Zfish   640 ---IREE----LLKILQELPSVS-----QETLKFSGIGRAVMYLYKHPKESRPN------KDLAL 686

  Fly   664 R 664
            :
Zfish   687 K 687