Protein Alignment CG12818 and LENG1

DIOPT Version :10

• Sequence 1: NP_649996.1
• Gene: CG12818 / 41261
• FlyBaseID: FBgn0037809
• Length: 288
• Species: Drosophila melanogaster
• Sequence 2: NP_077292.2
• Gene: LENG1 / 79165
• HGNCID: 15502
• Length: 264
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 103/292 - (35%)
• Similarity: 147/292 - (50%)
• Gaps: 45/292 - (15%)

  Fly     1 MNILPKKRWHVRTKENIARVRRDQAAAAAEEKVRQEKLEFAESEARINFLRR----QSGLPEKAS 61
            |||||||.||||.|:|:||||||:|.|..|||.|:.::..|:.|||..|||:    |:.|||
Human     1 MNILPKKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPE--- 62

  Fly    62 KESREESQCSTETTKGVDLFADYKARVKTT---NKDLEKEQKEEQEKYEKQIGYLTYLGQDTNEA 123
               .|.::.....:..||||.:.....|..   ||:.::|:::|:|:.||.:|.||||||...||
Human    63 ---LEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYKEEKRQEKERQEKALGILTYLGQSAAEA 124

  Fly   124 LKVRSWYELAPKRPEVGDPTATETHHKQKLAHDPLTLINALLPPEKKDPKKATKRIRERTPAPSQ 188
            .....||:|.|.|.  |.|.......|.|...|||              ::..|.:.::......
Human   125 QTQPPWYQLPPGRG--GPPPGPAPDEKIKSRLDPL--------------REMQKHLGKKRQHGGD 173

  Fly   189 EPSIPHKDKKSKKDKKKHKSKNGSRETLLAEERIKREKLETLRRERMRRETAERQRSEALFAPKE 253
            |.|   :.:|.|:..:|.:.|             :...|:.||.||:|||.|||.|:|||.|..:
Human   174 EGS---RSRKEKEGSEKQRPK-------------EPPSLDQLRAERLRREAAERSRAEALLARVQ 222

  Fly   254 LPVAASAESTPASTPKVVQKYNSQFNPELAKQ 285
            .......:.....|....::|||||||:||::
Human   223 GRALQEGQPEEDETDDRRRRYNSQFNPQLARR 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12818	NP_649996.1	Cir_N	8..44	CDD:198151	19/35 (54%)
LENG1	NP_077292.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37		25/35 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	49..76		8/32 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..264		49/169 (29%)
		FdhE	192..>262	CDD:450291	26/63 (41%)