DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bruce and RAD6

DIOPT Version :9

Sequence 1:	NP_001262460.1	Gene:	Bruce / 41260	FlyBaseID:	FBgn0266717	Length:	4976	Species:	Drosophila melanogaster
Sequence 2:	NP_011457.1	Gene:	RAD6 / 852822	SGDID:	S000003026	Length:	172	Species:	Saccharomyces cerevisiae

Alignment Length:	206	Identity:	55/206 - (26%)
Similarity:	91/206 - (44%)	Gaps:	56/206 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  4631 PSRVKRLAQEAVTLSTSLPLSFSSSVFVRCDTDRLDIMKVLITGPADTPYANGCFEFDVFFPPDY 4695
            |:| :||.::...:....|...|:|..    .|.:.:...:|.|||||||.:|.|...:.|..:|
Yeast     4 PAR-RRLMRDFKRMKEDAPPGVSASPL----PDNVMVWNAMIIGPADTPYEDGTFRLLLEFDEEY 63

  Fly  4696 PNQPMLINLETTGRHSVRFNPNLYNDGKVCLSVLNTWHGRPEEKWNAQTSSFLQVLVSIQSLILV 4760
            ||:|..:..     .|..|:||:|.:|::||.:|       :.:| ..|.....:|.|||||
Yeast    64 PNKPPHVKF-----LSEMFHPNVYANGEICLDIL-------QNRW-TPTYDVASILTSIQSL--- 112

  Fly  4761 PEPYFNEPGFERSRGSPSGTNSSREYNSNIYQACVRWAMLEQIRSPSQCFKDVIHKHFWLKREEI 4825
                ||:|    :..||          :|:..|.:              |||  ||..::||.:.
Yeast   113 ----FNDP----NPASP----------ANVEAATL--------------FKD--HKSQYVKRVKE 143

  Fly  4826 CAQIEGWIEEL 4836
            ..: :.|.:::
Yeast   144 TVE-KSWEDDM 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bruce	NP_001262460.1	BIR	251..321	CDD:279047
		DUF3643	3539..3664	CDD:289152
		UQ_con	4636..4790	CDD:278603	43/153 (28%)
RAD6	NP_011457.1	COG5078	1..150	CDD:227410	54/201 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910