DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bruce and ube2t

DIOPT Version :9

Sequence 1:	NP_001262460.1	Gene:	Bruce / 41260	FlyBaseID:	FBgn0266717	Length:	4976	Species:	Drosophila melanogaster
Sequence 2:	NP_001070763.1	Gene:	ube2t / 768152	ZFINID:	ZDB-GENE-061013-547	Length:	194	Species:	Danio rerio

Alignment Length:	212	Identity:	60/212 - (28%)
Similarity:	86/212 - (40%)	Gaps:	47/212 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  4633 RVKRLAQEAVTLSTSLPLSFSSSVFVRC--DTDRLDIMKVLITGPADTPYANGCFEFDVFFPPDY 4695
            ||.||.:|...|:...|..      |.|  ...|||.::..|.|.|:|||..|.|..::..|..|
Zfish     3 RVSRLKREMQLLTAEPPPG------VSCWQSEGRLDELQAQIVGGANTPYEGGVFTLEINIPERY 61

  Fly  4696 PNQPMLINLETTGRHSVRFNPNLYNDGKVCLSVLNTWHGRPEEKW----NAQTSSFLQVLVSIQS 4756
            |.:|..:...|...|     ||:.|.|::||..|..   .|:..|    |..|     ||.|||.
Zfish    62 PFEPPKMRFLTPIYH-----PNIDNAGRICLDALKL---PPKGAWRPSLNIST-----VLTSIQL 113

  Fly  4757 LILVPEPYFNEPGFERSRGSPSGTNSSREYNSNIY-QACVRWAMLEQIRSPSQCF---------K 4811
            |:..|.|  ::|       ..:..:|..:||..:| :...:|.....|:....|.         |
Zfish   114 LMAEPNP--DDP-------LMADISSEFKYNKPLYLEKAKKWTAEHAIQKNKGCVETDGKTPENK 169

  Fly  4812 DVIHKHFWLKREEICAQ 4828
            ::...|   |||.:.||
Zfish   170 NLKTSH---KREALSAQ 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bruce	NP_001262460.1	BIR	251..321	CDD:279047
		DUF3643	3539..3664	CDD:289152
		UQ_con	4636..4790	CDD:278603	47/159 (30%)
ube2t	NP_001070763.1	COG5078	1..152	CDD:227410	51/176 (29%)
		UBCc	4..147	CDD:238117	49/170 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	158..194		8/29 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910