DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bruce and ube2z

DIOPT Version :9

Sequence 1:	NP_001262460.1	Gene:	Bruce / 41260	FlyBaseID:	FBgn0266717	Length:	4976	Species:	Drosophila melanogaster
Sequence 2:	NP_001007969.2	Gene:	ube2z / 493338	XenbaseID:	XB-GENE-990986	Length:	313	Species:	Xenopus tropicalis

Alignment Length:	242	Identity:	88/242 - (36%)
Similarity:	122/242 - (50%)	Gaps:	30/242 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  4634 VKRLAQEAVTLSTSLPLSFSSSVFVRCDTDRLDIMKVLITGPADTPYANGCFEFDVFFPPDYPNQ 4698
            |.|:.::.:::....|    ..:||..|...:..:..|||||.||||..|.|.|....|||||..
Frog    60 VLRIKRDIMSIYKEPP----PGMFVVPDPHDMTKIHALITGPFDTPYEGGFFLFLFRCPPDYPIH 120

  Fly  4699 PMLINLETTGRHSVRFNPNLYNDGKVCLSVLNTWHGRPEEKWN-AQTSSFLQVLVSIQSLILVPE 4762
            |..:.|.|||.::||||||.|.:||||||:|.||.|   ..|: ||:.|  .||:||||| :...
Frog   121 PPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTG---PAWSPAQSLS--SVLISIQSL-MTEN 179

  Fly  4763 PYFNEPGFERSRGSPSGTNSSREYNSNIYQACVRWAMLEQIRSPSQC---FKDVIHKHF---WLK 4821
            ||.||||||:.|.|    ..|:.||..|....:|.|:.|.:....||   .:.|:.|.|   :..
Frog   180 PYHNEPGFEQERHS----GDSKNYNECIRHETIRVAVCEMLEGKCQCPDALRSVMEKSFMEYYDF 240

  Fly  4822 REEICA---QIEG------WIEELGKPQYTERASRTISFNSMVLRRH 4859
            .|.:|.   .::|      :.|:.|...|....||..:.:..|..:|
Frog   241 YEAVCKDRFHLQGQNMQDPFGEKRGHFDYQSLLSRLQTIHQRVREKH 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bruce	NP_001262460.1	BIR	251..321	CDD:279047
		DUF3643	3539..3664	CDD:289152
		UQ_con	4636..4790	CDD:278603	68/154 (44%)
ube2z	NP_001007969.2	UBCc	62..207	CDD:238117	69/158 (44%)
ube2z	NP_001007969.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	283..313		2/5 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1404665at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920