DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bruce and ube2a

DIOPT Version :9

Sequence 1:	NP_001262460.1	Gene:	Bruce / 41260	FlyBaseID:	FBgn0266717	Length:	4976	Species:	Drosophila melanogaster
Sequence 2:	NP_001004868.1	Gene:	ube2a / 448176	XenbaseID:	XB-GENE-969236	Length:	152	Species:	Xenopus tropicalis

Alignment Length:	172	Identity:	48/172 - (27%)
Similarity:	79/172 - (45%)	Gaps:	28/172 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  4631 PSRVKRLAQEAVTLSTSLPLSFSSSVFVRCDTDRLDIMKVLITGPADTPYANGCFEFDVFFPPDY 4695
            |:| :||.::...|....|...|.:.    ..:.:.:...:|.||..||:.:|.|:..:.|..:|
Frog     4 PAR-RRLMRDFKRLQEDPPAGVSGAP----SENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEY 63

  Fly  4696 PNQPMLINLETTGRHSVRFNPNLYNDGKVCLSVLNTWHGRPEEKWNAQTSSFLQVLVSIQSLILV 4760
            ||:|..:...     |..|:||:|.||.:||.:|       :.:| :.|.....:|.|||||:..
Frog    64 PNKPPTVRFV-----SKMFHPNVYADGSICLDIL-------QNRW-SPTYDVSSILTSIQSLLDE 115

  Fly  4761 PEPYFNEPGFERSRGSPSGTNSSREYNSNIYQACVRWAMLEQ 4802
            |.|  |.|.  .|:.:.....:.|||...:.      |::||
Frog   116 PNP--NSPA--NSQAAQLYQENKREYEKRVS------AIVEQ 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bruce	NP_001262460.1	BIR	251..321	CDD:279047
		DUF3643	3539..3664	CDD:289152
		UQ_con	4636..4790	CDD:278603	43/153 (28%)
ube2a	NP_001004868.1	UQ_con	8..145	CDD:395127	44/163 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910