Protein Alignment Bruce and birc2

DIOPT Version :9

• Sequence 1: NP_001262460.1
• Gene: Bruce / 41260
• FlyBaseID: FBgn0266717
• Length: 4976
• Species: Drosophila melanogaster
• Sequence 2: XP_005161213.1
• Gene: birc2 / 373107
• ZFINID: ZDB-GENE-030825-6
• Length: 647
• Species: Danio rerio
• Alignment Length: 552
• Identity: 115/552 - (20%)
• Similarity: 192/552 - (34%)
• Gaps: 156/552 - (28%)

  Fly   149 ECPCDISNELTQKINQAQ-LKAKKGIKAQRWNTICLEVPYSSLKLVSNNMVILLKRLERHIPVLA 212
            :||.:...:|:...:..| |.|...:         |...:|:...:.|..|:.|.......|...
Zfish    99 DCPAERHKQLSPNCSFIQSLPATANL---------LSSSHSAFSPLRNVAVLQLSAPATAAPSTT 154

  Fly   213 IASA----------INERLTDMMMGSRVPDFGWNFSNFQR-VLMHSEAVRRQ-----TFEKWPHM 261
            ..|.          :|...|::...|.:...|....:.|| ...|:..:||:     ||:.|
Zfish   155 APSTSGQTEEQVGYLNMGFTNLAPSSPISSRGVEDMSHQRPPACHNPGMRREQERLDTFQNW--- 216

  Fly   262 DYKWALPDQMAQAGFYHQPSSSGEDRAMCFTCSVCLVCWEKTDEPWSEHERHSPLCPFVKGEYTQ 326
            ......|.::|:||.|:....   ||..||:|...|..||..|...|||:||.|.|.||:|:...
Zfish   217 TLATVTPAELAKAGLYYLGQG---DRVACFSCGGQLGSWEPGDRAVSEHQRHYPNCRFVRGDRAD 278

  Fly   327 NVPLSITYATNPALPAPGLGFDIISNSDYANVLCTSCSQTGELSVWSIERHLKLMHTFHVPTLLN 391
            |:|||            |.|...:|||     ....|.:                      .||.
Zfish   279 NIPLS------------GGGLSNVSNS-----AMQQCEE----------------------RLLT 304

  Fly   392 YIFEESFEWARVTAICVLPNARARTKVNYVYSAANYGGSGSSNGAGCNSGLNAVSGG-------- 448
            ::     .|.  :.|.|.|:..|:....||      |.:.......|:.||.....|
Zfish   305 FV-----NWP--SRIPVRPDQLAKAGFYYV------GRNDDVKCFCCDGGLRCWESGDDPWVEHA 356

  Fly   449 -----------------------KFGSVNAQHITSTSTLRAGVVGSKIV-LGVSVRQSSGELALR 489
                                   :|..:..|.:|:..:.....|...:| ||....:|...:.:.
Zfish   357 KWFPRCEYLLQEKGQEFVHQIQARFPRLFEQLLTNGDSNSREFVDPPVVHLGPGEDRSEDAVMMN 421

  Fly   490 MVVLNIVEVDRNSESSTSVSNDSGSVSSGGGQLMKSSSPMVNVSAENNATVTQV--NLESKDDDN 552
            ..|:         :|:..:..:.|.|.    |.::|.   :..|.||..||.::  :|.|.:|:
Zfish   422 NPVV---------KSALEMGFERGLVK----QTVQSK---ILTSGENYKTVQELVSDLLSAEDE- 469

  Fly   553 KAMTPYEKFADGFDSNGFVSALMTYNKNN--GVSQNTDDASALYDFDLCTLSQILDHNLEEPLSL 615
            |.....|..|:...|:||     |:.|.:  .:||.           |.::..::||.|||.
Zfish   470 KREEERELLAEEMASDGF-----TFLKKHHAALSQR-----------LKSVQSLMDHLLEEN--- 515

  Fly   616 MVGSSNTVNVSNIGMGNEINKLVVDVEISHQN 647
            ::......::.|.....:....::|:.:|..|
Zfish   516 VISQKEYDSIRNCTSVKQQTGQLIDLVLSKGN 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bruce	NP_001262460.1	BIR	251..321	CDD:279047	27/74 (36%)
		DUF3643	3539..3664	CDD:289152
		UQ_con	4636..4790	CDD:278603
birc2	XP_005161213.1	BIR	51..117	CDD:237989	3/17 (18%)
		BIR	206..274	CDD:197595	26/73 (36%)
		BIR	299..366	CDD:237989	14/101 (14%)
		UBA_BIRC2_3	420..466	CDD:270577	12/61 (20%)
		CARD_BIRC2_BIRC3	482..573	CDD:260038	17/85 (20%)
		zf-C3HC4_3	596..641	CDD:290631

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810