DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bruce and Ube2b

DIOPT Version :9

Sequence 1:	NP_001262460.1	Gene:	Bruce / 41260	FlyBaseID:	FBgn0266717	Length:	4976	Species:	Drosophila melanogaster
Sequence 2:	NP_001349614.1	Gene:	Ube2b / 22210	MGIID:	102944	Length:	152	Species:	Mus musculus

Alignment Length:	174	Identity:	50/174 - (28%)
Similarity:	81/174 - (46%)	Gaps:	32/174 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly  4631 PSRVKRLAQEAVTLSTSLPLSFSSSVFVRCDTDRLDIMK--VLITGPADTPYANGCFEFDVFFPP 4693
            |:| :||.::...|....|:..|.:      ....:||:  .:|.||..||:.:|.|:..:.|..
Mouse     4 PAR-RRLMRDFKRLQEDPPVGVSGA------PSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFSE 61

  Fly  4694 DYPNQPMLINLETTGRHSVRFNPNLYNDGKVCLSVLNTWHGRPEEKWNAQTSSFLQVLVSIQSLI 4758
            :|||:|..:..     .|..|:||:|.||.:||.:|       :.:| :.|.....:|.|||||:
Mouse    62 EYPNKPPTVRF-----LSKMFHPNVYADGSICLDIL-------QNRW-SPTYDVSSILTSIQSLL 113

  Fly  4759 LVPEPYFNEPGFERSRGSPSGTNSSREYNSNIYQACVRWAMLEQ 4802
            ..|.|  |.|.  .|:.:.....:.|||...:.      |::||
Mouse   114 DEPNP--NSPA--NSQAAQLYQENKREYEKRVS------AIVEQ 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bruce	NP_001262460.1	BIR	251..321	CDD:279047
		DUF3643	3539..3664	CDD:289152
		UQ_con	4636..4790	CDD:278603	45/155 (29%)
Ube2b	NP_001349614.1	UQ_con	8..145	CDD:395127	46/165 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910