Protein Alignment Bruce and ubc-17

DIOPT Version :9

• Sequence 1: NP_001262460.1
• Gene: Bruce / 41260
• FlyBaseID: FBgn0266717
• Length: 4976
• Species: Drosophila melanogaster
• Sequence 2: NP_509188.3
• Gene: ubc-17 / 181979
• WormBaseID: WBGene00006712
• Length: 728
• Species: Caenorhabditis elegans
• Alignment Length: 647
• Identity: 209/647 - (32%)
• Similarity: 306/647 - (47%)
• Gaps: 125/647 - (19%)

  Fly  4273 RRVVIEVGAMHLVLNCLGIFSHQSHNNRIGAPISEPSPSGTSSGSGTIGNGSGNGSVSGTKTNAP 4337
            |:..:|.|.:|.:|..:|           ...||:.|.|..|:..              .|..|.
 Worm    96 RKQFVECGVIHHLLELIG-----------ETAISDFSASSRSADE--------------QKRRAR 135

  Fly  4338 EEATPSATSDDKSHMYWAKGTGFGTGSTTQSWNVEQALLRQKSEEEHVTVLLLVLASYINPGDCI 4402
            ..::.|.     ||    ||||:|||||...|::|:.:..:...|||:|.||.:|.|:
 Worm   136 RNSSASL-----SH----KGTGYGTGSTRSRWDIERTVEEKLIREEHLTWLLSILNSF------- 184

  Fly  4403 PSEMCG-----------EDILAYHDVRDVTGELPPIFQTLLQQSCLIPALSSYLRNDSVLDITRH 4456
               |.|           |:::          .:..|...|:..|.::..|...|||||..|::.|
 Worm   185 ---MLGWPTTDNLKTKPEELV----------HMTEIAIKLIADSSVLSILEYNLRNDSFFDVSEH 236

  Fly  4457 IPLYRAILKLLRALSLSKMLVSLLQPSASGSGDSTPPIVELLTSMKT-CVDTYAKRLKVNKKSNI 4520
            |.:|:|:|:...:::                  :||.:|..|....| ...:.||.|....|.||
 Worm   237 IEIYQALLETAASMA------------------ATPGLVPFLVRPYTSSAKSIAKELIPRFKENI 283

  Fly  4521 -------KGQTHQLTFNIDDGDDEGLALLIPDIHETSVLVQKTTDADALINM----------LHT 4568
                   .|...:..|.:.:...: :.||...:...:...::|...:..|..          ||:
 Worm   284 LSIQARWGGTLEETNFRMAEFTAK-VTLLSDYVINAARAYEQTLPPEQRIQTATHRRPSHSGLHS 347

  Fly  4569 NEDGSAQLEPQSKSIEQRYLELMKKRQFDTFDMIVESDNNSFRFVVSHHFEKMVRLAGDRYHP-- 4631
            ...|       .|..|..|...|::.|..|...|    .:..:..|.:.|.|..:.. :.:.|
 Worm   348 KMQG-------PKDDETIYKNKMQELQLQTAKFI----GDFGKLCVPYVFRKEAKNI-NPFSPHL 400

  Fly  4632 -SRVKRLAQEAVTLSTSLPLSFSSSVFVRCDTDRLDIMKVLITGPADTPYANGCFEFDVFFPPDY 4695
             .|.||:|:|..:::.:|||:.|:|::|..|..|:||:||||:||.|||||||.||||:|||..|
 Worm   401 RDRTKRIAKELASIANALPLNASNSIYVCYDEGRVDIIKVLISGPDDTPYANGLFEFDIFFPTGY 465

  Fly  4696 PNQPMLINLETTGRHSVRFNPNLYNDGKVCLSVLNTWHGRPEEKWNAQTSSFLQVLVSIQSLILV 4760
            |..|......|||..:||||||||||||:|||:|.||.||||||||.. .|.:|||||||.||.|
 Worm   466 PFSPPKCAFLTTGSGNVRFNPNLYNDGKICLSILGTWEGRPEEKWNPY-CSLMQVLVSIQGLIFV 529

  Fly  4761 PEPYFNEPGFERSRGSPSGTNSSREYNSNIYQACVRWAMLEQIRSPSQCFKDVIHKHFWLKREEI 4825
            .:||||||||||.:|:..|...||:||..|..|.:.:|:.||::.||:.||:||.||.|||||.|
 Worm   530 KDPYFNEPGFERYQGTDRGDEYSRKYNLQIEHATLNYAIREQLKKPSEHFKEVIEKHLWLKREAI 594

  Fly  4826 CAQIEGWIEELGKPQYTERASR-------TISFNSMVLRRHYRHLREELSKLKPPRGLEDLD 4880
            ..|.:.||:.:......::.|:       ...||.....|...:|.:||..::.|...|:.:
 Worm   595 LKQAQAWIDNVSNDFGDDKMSKRKDVFAFETGFNPATQERVIHNLIQELQAMQSPFAKEEAE 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bruce	NP_001262460.1	BIR	251..321	CDD:279047
		DUF3643	3539..3664	CDD:289152
		UQ_con	4636..4790	CDD:278603	92/153 (60%)
ubc-17	NP_509188.3	UBCc	406..>527	CDD:214562	73/121 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163327
Domainoid	1	1.000	193	1.000	Domainoid score	I1866
eggNOG	1	0.900	-	-		E2759_KOG0895
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto20520
orthoMCL	1	0.900	-	-		OOG6_104392
Panther	1	1.100	-	-	LDO	PTHR46116
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2875
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.770