Protein Alignment Bruce and ubc-17

DIOPT Version :10

• Sequence 1: NP_001262460.1
• Gene: Bruce / 41260
• FlyBaseID: FBgn0266717
• Length: 4976
• Species: Drosophila melanogaster
• Sequence 2: NP_509188.3
• Gene: ubc-17 / 181979
• WormBaseID: WBGene00006712
• Length: 728
• Species: Caenorhabditis elegans
• Alignment Length: 647
• Identity: 209/647 - (32%)
• Similarity: 306/647 - (47%)
• Gaps: 125/647 - (19%)

  Fly  4273 RRVVIEVGAMHLVLNCLGIFSHQSHNNRIGAPISEPSPSGTSSGSGTIGNGSGNGSVSGTKTNAP 4337
            |:..:|.|.:|.:|..:|           ...||:.|.|..|:..              .|..|.
 Worm    96 RKQFVECGVIHHLLELIG-----------ETAISDFSASSRSADE--------------QKRRAR 135

  Fly  4338 EEATPSATSDDKSHMYWAKGTGFGTGSTTQSWNVEQALLRQKSEEEHVTVLLLVLASYINPGDCI 4402
            ..::.|.     ||    ||||:|||||...|::|:.:..:...|||:|.||.:|.|:
 Worm   136 RNSSASL-----SH----KGTGYGTGSTRSRWDIERTVEEKLIREEHLTWLLSILNSF------- 184

  Fly  4403 PSEMCG-----------EDILAYHDVRDVTGELPPIFQTLLQQSCLIPALSSYLRNDSVLDITRH 4456
               |.|           |:::          .:..|...|:..|.::..|...|||||..|::.|
 Worm   185 ---MLGWPTTDNLKTKPEELV----------HMTEIAIKLIADSSVLSILEYNLRNDSFFDVSEH 236

  Fly  4457 IPLYRAILKLLRALSLSKMLVSLLQPSASGSGDSTPPIVELLTSMKT-CVDTYAKRLKVNKKSNI 4520
            |.:|:|:|:...:::                  :||.:|..|....| ...:.||.|....|.||
 Worm   237 IEIYQALLETAASMA------------------ATPGLVPFLVRPYTSSAKSIAKELIPRFKENI 283

  Fly  4521 -------KGQTHQLTFNIDDGDDEGLALLIPDIHETSVLVQKTTDADALINM----------LHT 4568
                   .|...:..|.:.:...: :.||...:...:...::|...:..|..          ||:
 Worm   284 LSIQARWGGTLEETNFRMAEFTAK-VTLLSDYVINAARAYEQTLPPEQRIQTATHRRPSHSGLHS 347

  Fly  4569 NEDGSAQLEPQSKSIEQRYLELMKKRQFDTFDMIVESDNNSFRFVVSHHFEKMVRLAGDRYHP-- 4631
            ...|       .|..|..|...|::.|..|...|    .:..:..|.:.|.|..:.. :.:.|
 Worm   348 KMQG-------PKDDETIYKNKMQELQLQTAKFI----GDFGKLCVPYVFRKEAKNI-NPFSPHL 400

  Fly  4632 -SRVKRLAQEAVTLSTSLPLSFSSSVFVRCDTDRLDIMKVLITGPADTPYANGCFEFDVFFPPDY 4695
             .|.||:|:|..:::.:|||:.|:|::|..|..|:||:||||:||.|||||||.||||:|||..|
 Worm   401 RDRTKRIAKELASIANALPLNASNSIYVCYDEGRVDIIKVLISGPDDTPYANGLFEFDIFFPTGY 465

  Fly  4696 PNQPMLINLETTGRHSVRFNPNLYNDGKVCLSVLNTWHGRPEEKWNAQTSSFLQVLVSIQSLILV 4760
            |..|......|||..:||||||||||||:|||:|.||.||||||||.. .|.:|||||||.||.|
 Worm   466 PFSPPKCAFLTTGSGNVRFNPNLYNDGKICLSILGTWEGRPEEKWNPY-CSLMQVLVSIQGLIFV 529

  Fly  4761 PEPYFNEPGFERSRGSPSGTNSSREYNSNIYQACVRWAMLEQIRSPSQCFKDVIHKHFWLKREEI 4825
            .:||||||||||.:|:..|...||:||..|..|.:.:|:.||::.||:.||:||.||.|||||.|
 Worm   530 KDPYFNEPGFERYQGTDRGDEYSRKYNLQIEHATLNYAIREQLKKPSEHFKEVIEKHLWLKREAI 594

  Fly  4826 CAQIEGWIEELGKPQYTERASR-------TISFNSMVLRRHYRHLREELSKLKPPRGLEDLD 4880
            ..|.:.||:.:......::.|:       ...||.....|...:|.:||..::.|...|:.:
 Worm   595 LKQAQAWIDNVSNDFGDDKMSKRKDVFAFETGFNPATQERVIHNLIQELQAMQSPFAKEEAE 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bruce	NP_001262460.1	BIR	251..321	CDD:459891
		BIRC6	3539..3664	CDD:463547
		UBCc_BIRC6	4631..4835	CDD:467430	117/206 (57%)
ubc-17	NP_509188.3	UBCc_BIRC6	401..602	CDD:467430	114/201 (57%)