Protein Alignment Bruce and bir-2

DIOPT Version :10

• Sequence 1: NP_001262460.1
• Gene: Bruce / 41260
• FlyBaseID: FBgn0266717
• Length: 4976
• Species: Drosophila melanogaster
• Sequence 2: NP_506362.1
• Gene: bir-2 / 179841
• WormBaseID: WBGene00000250
• Length: 308
• Species: Caenorhabditis elegans
• Alignment Length: 223
• Identity: 59/223 - (26%)
• Similarity: 88/223 - (39%)
• Gaps: 53/223 - (23%)

  Fly   185 VPYSSLKLVSNNMVILLKRLERHIPVLAIASAINERLTDMMMGSRVPDFGWNFSNFQRVLMHSEA 249
            :||:     ..|...|||.|:...|.::.|    ||                |::|:..:.....
 Worm     1 MPYT-----FENSEALLKNLKDAAPYISAA----ER----------------FASFKGFVYDKRI 40

  Fly   250 VRRQTFEKWPHMDYKWALPDQMAQAGFYHQPSSSGEDRAMCFTCSVCLVCWEKTDEPWSEHERHS 314
            ....|.||             :|:||||...|......|.|..| :..:.:|:.|:||.:|:..|
 Worm    41 NIACTSEK-------------LARAGFYSTASPEFPASAKCPFC-MLEINFEQCDDPWEKHKSGS 91

  Fly   315 PLCPFVK-GEYTQN-------VPLSITYATNPALPAPGLGF-DIISNSDYANV-LCTSCSQTGEL 369
            |.|.||. ||..::       ..|:|.:|| ..|....||. ..:.|.|.||. ..|....|.:|
 Worm    92 PHCEFVMIGEIEESELSFRIISNLAIRHAT-VRLYEELLGIVATLENGDIANENPITRADATRKL 155

  Fly   370 SVWSIERHLKLMHTFH-VPTLLNYIFEE 396
            .  |.....||:...| :.|..|:||::
 Worm   156 I--SFRSSSKLLTFDHRLATFQNFIFDK 181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bruce	NP_001262460.1	BIR	251..321	CDD:459891	21/69 (30%)
		BIRC6	3539..3664	CDD:463547
		UBCc_BIRC6	4631..4835	CDD:467430
bir-2	NP_506362.1	BIR	23..99	CDD:197595	27/109 (25%)
		BIR	166..242	CDD:197595	5/16 (31%)