DRSC/TRiP Functional Genomics Resources

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Protein Alignment Bruce and Birc2

DIOPT Version :9

Sequence 1:NP_001262460.1 Gene:Bruce / 41260 FlyBaseID:FBgn0266717 Length:4976 Species:Drosophila melanogaster
Sequence 2:NP_001278432.1 Gene:Birc2 / 11797 MGIID:1197009 Length:612 Species:Mus musculus


Alignment Length:323 Identity:77/323 - (23%)
Similarity:120/323 - (37%) Gaps:73/323 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   109 LDTILQAPIGQNDDYIKLEIILSEAIIFQNCITELESE-GLECPCDISNELTQK-------INQA 165
            :|..:...:||...:.||:.|:.::.|..|...|.|.: ..:..|::....|..       :::.
Mouse     1 MDKTVSQRLGQGTLHQKLKRIMEKSTILSNWTKESEEKMKFDFSCELYRMSTYSAFPRGVPVSER 65

  Fly   166 QL------------KAK---KGIKAQRWN----------------TICLEVPYSSLKLVSNNMVI 199
            .|            |.|   .|:....|.                :....:..:||:..|.||..
Mouse    66 SLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDSPVEKHRQFYPSCSFVQTLLSASLQSPSKNMSP 130

  Fly   200 LLKRLERHIPVLAIASAINERLTDMMMGSR-VPDFGWNFSNFQRVLMHSEAVRRQTFEKWPHMDY 263
            :..|.....|:  ....|:..|....:.|| |.||........ ..|.:|..|..|:..||   .
Mouse   131 VKSRFAHSSPL--ERGGIHSNLCSSPLNSRAVEDFSSRMDPCS-YAMSTEEARFLTYSMWP---L 189

  Fly   264 KWALPDQMAQAGFYH-QPSSSGEDRAMCFTCSVCLVCWEKTDEPWSEHERHSPLCPFVKG-EYTQ 326
            .:..|.::|:||||: .|.    ||..||.|...|..||..|:..|||.||.|.|||::. ..||
Mouse   190 SFLSPAELARAGFYYIGPG----DRVACFACGGKLSNWEPKDDAMSEHRRHFPHCPFLENTSETQ 250

  Fly   327 NVPLS-ITYATN-----------PALPA-----PGLGFDIISNSDYANVLCTSCSQTGELSVW 372
            ...:| ::..|:           |::|.     ...||..:..:|  :|.|..|.  |.|..|
Mouse   251 RFSISNLSMQTHSARLRTFLYWPPSVPVQPEQLASAGFYYVDRND--DVKCFCCD--GGLRCW 309

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BruceNP_001262460.1 BIR 251..321 CDD:279047 29/70 (41%)
DUF3643 3539..3664 CDD:289152
UQ_con 4636..4790 CDD:278603
Birc2NP_001278432.1 BIR 45..114 CDD:197595 7/68 (10%)
BIR 1 46..113 6/66 (9%)
BIR 176..245 CDD:197595 30/75 (40%)
BIR 2 177..243 29/72 (40%)
BIR 3 262..329 11/52 (21%)
BIR 263..329 CDD:237989 11/51 (22%)
UBA_BIRC2_3 385..431 CDD:270577
CARD_BIRC2_BIRC3 447..538 CDD:260038
RING-HC_BIRC2_3_7 559..612 CDD:319627
RING-HC finger (C3HC4-type) 565..599 CDD:319627
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1101
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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