Protein Alignment CG6293 and SLC23A1

DIOPT Version :9

• Sequence 1: NP_001262459.1
• Gene: CG6293 / 41259
• FlyBaseID: FBgn0037807
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: XP_005272205.3
• Gene: SLC23A1 / 9963
• HGNCID: 10974
• Length: 638
• Species: Homo sapiens
• Alignment Length: 571
• Identity: 251/571 - (43%)
• Similarity: 358/571 - (62%)
• Gaps: 13/571 - (2%)

  Fly     9 EDATDASKSYSQAANTPPSNEKPKPQLLYAINDNPPWYLSIFLAFQHYLTMIGAIVSIPFILTPA 73
            ||....::..:....:.|...:||..:||.|.|.|||||.|.|.||||||.....:::||:|..|
Human    41 EDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEA 105

  Fly    74 LCMSDEDANRGIIISTMIFVTGIVTYFQATWGVRLPIVQGGTISFLVPTLAILALPQWKCP--EQ 136
            ||:..:......:|.|:....||.|..|.|.|:|||:.|....:||||..|||||.:||||  |:
Human   106 LCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEE 170

  Fly   137 AVMDAMDEAEREELWQVRMRE----LSGAIAVSAMVQVILGYTGLVGKILKYVTPLTIVPTVSLV 197
            ...:.........:|..|:||    :.|||.||::|:|::|..||.|.:|.|:.|||:.|||||:
Human   171 IYGNWSLPLNTSHIWHPRIREVGLHVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVSLI 235

  Fly   198 GLTLFEHAAETASKHWGIAVGTTGMLTLFSQIMSNVPVPILAYRKGHGLEIRQFQLFRLFPVLLT 262
            ||::|:.|.:.|..||||:..:..::.||||.:.|:...:..||.|.||.:.:.|:|::||::|.
Human   236 GLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRIQIFKMFPIMLA 300

  Fly   263 IMIMWGLCGILTATDVFPP-----SHPSRTDVRLNVLTSAKWFYVPYPGQFGWPSVTLSGVLGML 322
            ||.:|.||.:||.|||.|.     ...:|||.|.:::..|.|..:|||.|:|.|:||.:.||||.
Human   301 IMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMF 365

  Fly   323 AGVLACTVESLSYYPTVSQMSGAHSPPLHAINRGIGTEGFGTVLAGLWGAGNGTNTFGENVGAIG 387
            :..||..:||:..|...::::||..||:|||||||.|||...::|||.|.|||:.:...|:|.:|
Human   366 SATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLG 430

  Fly   388 VTKIGSRRVIQWAALIMVLQGVIGKFGAIFILIPDSVVGGIFCVMFGMIIAFGLSTLQYVDLRSA 452
            :||:|||||:|:.|.||::.|.||||.|:|..:||.::||:||.:||||.|.|||.||:||:.|:
Human   431 ITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSS 495

  Fly   453 RNLYILGLSIFFPMVLCRWMQKNPGAIDTGNKTVDSTLSVLLGTTILVGGVLGCLLDNIIPGTPE 517
            |||::||.|:||.:.|..:::.|||||:||...||..|.|||.|.:.|||.|..:|||.:||:||
Human   496 RNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPE 560

  Fly   518 ERGLIDWANEMPLGDDNVNDGTATDYDFPLGMDAIRRWKWTYYIPFMPTYK 568
            |||||.|........|  ...:...||||:||..::|..:..|||..|.:|
Human   561 ERGLIQWKAGAHANSD--MSSSLKSYDFPIGMGIVKRITFLKYIPICPVFK 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6293	NP_001262459.1	HCO3_cotransp	32..519	CDD:304903	228/497 (46%)
		Xan_ur_permease	48..464	CDD:279232	190/426 (45%)
SLC23A1	XP_005272205.3	HCO3_cotransp	64..522	CDD:304903	206/457 (45%)
		Xan_ur_permease	81..516	CDD:279232	193/434 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	410	1.000	Domainoid score	I686
eggNOG	1	0.900	-	-		E1_COG2233
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	507	1.000	Inparanoid score	I1340
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61611
OrthoDB	1	1.010	-	-		D219070at33208
OrthoFinder	1	1.000	-	-		FOG0000230
OrthoInspector	1	1.000	-	-		otm41345
orthoMCL	1	0.900	-	-		OOG6_100583
Panther	1	1.100	-	-	O	PTHR11119
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1881
SonicParanoid	1	1.000	-	-		X261
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.870