DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6293 and AT1G65550

DIOPT Version :9

Sequence 1:	NP_001262459.1	Gene:	CG6293 / 41259	FlyBaseID:	FBgn0037807	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_176733.2	Gene:	AT1G65550 / 842866	AraportID:	AT1G65550	Length:	541	Species:	Arabidopsis thaliana

Alignment Length:	518	Identity:	148/518 - (28%)
Similarity:	258/518 - (49%)	Gaps:	46/518 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 TDASKSYSQAAN-----TPPSNEKPKPQLLYAINDNPPWYLSIFLAFQHYLTMIGAIVSIPFILT 71
            |:.....:.|||     .|...::..|.:.|.:|..|||..::.|.|||||..:|..|.||.:|.
plant     2 TNGGGGNNGAANRTEELQPHPVKEQLPGIQYCVNSPPPWLEAVVLGFQHYLLSLGITVLIPSVLV 66

  Fly    72 PALCMSDEDANRGIIISTMIFVTGIVTYFQATWGVRLPIVQGGTISFLVPTLAILALPQWKCPEQ 136
            |  .|....|.:..:|.|::||:|:.|.||:.:|.|||::...:.::::|..:|:...::..
plant    67 P--LMGGGYAEKVKVIQTLLFVSGLTTLFQSFFGTRLPVIAVASYAYIIPITSIIYSTRFTY--- 126

  Fly   137 AVMDAMDEAEREELWQVR-MRELSGAIAVSAMVQVILGYTGLVGKILKYVTPLTIVPTVSLVGLT 200
                ..|..||    .|| ||.:.||:.::...||::...|:...|:::::||:|.|..:..||.
plant   127 ----YTDPFER----FVRTMRSIQGALIITGCFQVLICILGVWRNIVRFLSPLSIAPLATFTGLG 183

  Fly   201 LFEHAAETASKHWG-------IAVGTTGMLTLFSQIMSNVPVPILAYRKGHGLEIRQFQLFRLFP 258
            |:         |.|       :.||..|::.|.. :...:| ..|..:|  |:.|........:.
plant   184 LY---------HIGFPLLARCVEVGLPGLILLIF-VTQYLP-RFLKMKK--GVMILDGSRCDRYG 235

  Fly   259 VLLTIMIMWGLCGILTATDVFP-PSHPSRTDVRLN---VLTSAKWFYVPYPGQFGWPSVTLSGVL 319
            ::|.|.::|....:||::.|:. .||.::|..|.:   ::|:..|.|:|||.|:|.|:..::...
plant   236 MILCIPLVWLFAQLLTSSGVYDHKSHTTQTSCRTDRTGLITNTPWIYIPYPFQWGSPTFDITDSF 300

  Fly   320 GMLAGVLACTVESLSYYPTVSQMSGAHSPPLHAINRGIGTEGFGTVLAGLWGAGNGTNTFGENVG 384
            .|:|.......||...:...::...|...|...::||....|.|.:|.|:.|...|..|..||||
plant   301 AMMAASFVTLFESTGLFYASARYGSATPIPPSVVSRGTCWLGVGVLLNGMLGGITGITTSTENVG 365

  Fly   385 AIGVTKIGSRRVIQWAALIMVLQGVIGKFGAIFILIPDSVVGGIFCVMFGMIIAFGLSTLQYVDL 449
            .:.:||||||||||.:|..|:...:.|||||.|..||..::..::|::...:.:.|||.||:.:|
plant   366 LLAMTKIGSRRVIQISAAFMIFFSIFGKFGAFFASIPLPIMASLYCIVLCFVSSVGLSYLQFCNL 430

  Fly   450 RSARNLYILGLSIFFPMVLCRWMQK--NPG-AIDTGNKTVDSTLSVLLGTTILVGGVLGCLLD 509
            .|....:|||.|.|..:.:.::.::  |.| ..|..:..::..:.|:..:...|..::..:||
plant   431 NSFNIKFILGFSFFMAISIPQYFREYYNGGWRSDHHSNWLEDMIRVIFMSHTTVAAIIAIVLD 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6293	NP_001262459.1	HCO3_cotransp	32..519	CDD:304903	143/493 (29%)
CG6293	NP_001262459.1	Xan_ur_permease	48..464	CDD:279232	129/427 (30%)
AT1G65550	NP_176733.2	HCO3_cotransp	34..493	CDD:304903	139/484 (29%)
AT1G65550	NP_176733.2	Xan_ur_permease	41..455	CDD:279232	130/439 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	262	1.000	Domainoid score	I473
eggNOG	1	0.900	-	-		E1_COG2233
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	291	1.000	Inparanoid score	I827
OMA	1	1.010	-	-		QHG61611
OrthoDB	1	1.010	-	-		D387031at2759
OrthoFinder	1	1.000	-	-		FOG0000230
OrthoInspector	1	1.000	-	-		otm2430
orthoMCL	1	0.900	-	-		OOG6_100583
Panther	1	1.100	-	-	O	PTHR11119
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X261
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840