DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6293 and NAT8

DIOPT Version :9

Sequence 1:	NP_001262459.1	Gene:	CG6293 / 41259	FlyBaseID:	FBgn0037807	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_172524.1	Gene:	NAT8 / 837595	AraportID:	AT1G10540	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	549	Identity:	176/549 - (32%)
Similarity:	285/549 - (51%)	Gaps:	51/549 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PPSNE---KPKP------QLLYAINDNPPWYLSIFLAFQHYLTMIGAIVSIPFILTPALCMSDED 80
            ||..:   :|.|      .:.|.:...|||..:|.|.|||||.|:|..|.||.:|...:...:||
plant    11 PPQKQEDLQPHPVKDQLYGITYCLTSPPPWPETILLGFQHYLVMLGTTVLIPTMLVSKIDARNED 75

  Fly    81 ANRGIIISTMIFVTGIVTYFQATWGVRLPIVQGGTISFLVPTLAILALPQWKCPEQAVMDAMDEA 145
            ..:  :|.|::||:||.|.||:.:|.|||.|.|.:.|::..|::|:...::.       |.||..
plant    76 KVK--LIQTLLFVSGINTLFQSFFGTRLPAVIGASYSYVPTTMSIVLAARYN-------DIMDPQ 131

  Fly   146 EREELWQVRMRELSGAIAVSAMVQVILGYTGLVGKILKYVTPLTIVPTVSLVGLTLFEHAAETAS 210
            :|.|  |: ||.:.||:.:::.:.:::|::||...:.::::||:.||.|:..|..|:|......:
plant   132 KRFE--QI-MRGIQGALIIASFLHILVGFSGLWRNVTRFLSPLSAVPLVAFSGFGLYEQGFPMLA 193

  Fly   211 KHWGIAVGTTGMLTLFSQIMSNVPVPILAYRKGHGLEIRQFQLFRLFPVLLTIMIMWGLCGILTA 275
            |...|.:....:|.:|||.     :|.|.    .|.....|  |..|.|:.:::|:|....|||.
plant   194 KCIEIGLPEIILLVIFSQY-----IPHLM----QGETCSNF--FHRFAVIFSVVIVWLYAYILTI 247

  Fly   276 TDVFPPSH-----PSRTDVRLNVLTSAKWFYVPYPGQFGW-PSVTLSGVLGMLAGVLACTVESLS 334
            ...:..:.     ..||| |..:::::.|..||:|.|:|. |:.....:..|:|......|||..
plant   248 GGAYSNTEINTQISCRTD-RAGIISASPWIRVPHPIQWGGAPTFNAGDIFAMMAASFVSLVESTG 311

  Fly   335 YYPTVSQMSGAHSPPLHAINRGIGTEGFGTVLAGLWGAGNGTNTFGENVGAIGVTKIGSRRVIQW 399
            .|..||:.:.|...|...::||||.:|||.:|.||:||||.|:...||.|.:.||::|||||||.
plant   312 TYIAVSRYASATPIPPSVLSRGIGWQGFGILLCGLFGAGNATSVSVENAGLLAVTRVGSRRVIQV 376

  Fly   400 AALIMVLQGVIGKFGAIFILIPDSVVGGIFCVMFGMIIAFGLSTLQYVDLRSARNLYILGLSIFF 464
            ||..|:...::|||||||..||..:|..::|:.|..:.|.|||.:|:.:|.|.|..:|||.|||.
plant   377 AAGFMIFFSILGKFGAIFASIPAPIVAALYCLFFSYVGAGGLSLIQFCNLNSFRTKFILGFSIFM 441

  Fly   465 PMVLCRWMQ-----KNPGAIDTGNKTVDSTLSVLLGTTILVGGVLGCLLDNIIP----GTPEERG 520
            .:.:.::..     :..|.:.|.....::.::|...:...|.|:|...||..:|    .|.::||
plant   442 GLSIPQYFYQYTTLETYGPVRTSATWFNNIINVPFSSKAFVSGILAFFLDTTLPPKDKTTKKDRG 506

  Fly   521 LIDWANEMPLGDDNVNDGTATDYDFPLGM 549
            |:.|........||.::   ..|..||.:
plant   507 LVWWKRFKSFQSDNRSE---EFYSLPLNL 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6293	NP_001262459.1	HCO3_cotransp	32..519	CDD:304903	164/507 (32%)
CG6293	NP_001262459.1	Xan_ur_permease	48..464	CDD:279232	148/421 (35%)
NAT8	NP_172524.1	Xan_ur_permease	41..449	CDD:419983	149/431 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	262	1.000	Domainoid score	I473
eggNOG	1	0.900	-	-		E1_COG2233
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	291	1.000	Inparanoid score	I827
OMA	1	1.010	-	-		QHG61611
OrthoDB	1	1.010	-	-		D387031at2759
OrthoFinder	1	1.000	-	-		FOG0000230
OrthoInspector	1	1.000	-	-		otm2430
orthoMCL	1	0.900	-	-		OOG6_100583
Panther	1	1.100	-	-	O	PTHR11119
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X261
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840