DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6293 and AT5G62890

DIOPT Version :9

Sequence 1:	NP_001262459.1	Gene:	CG6293 / 41259	FlyBaseID:	FBgn0037807	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_001032127.2	Gene:	AT5G62890 / 836409	AraportID:	AT5G62890	Length:	532	Species:	Arabidopsis thaliana

Alignment Length:	516	Identity:	160/516 - (31%)
Similarity:	262/516 - (50%)	Gaps:	43/516 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PSNEKPK---PQLLYAINDNPPWYLSIFLAFQHYLTMIGAIVSIPFILTPALCMSDEDANRGIII 87
            |....||   |.:.|.|...|||..:|.|.|||||.|:|..|.||..|.|.:....|:  :..:|
plant    14 PQPHPPKDQLPNISYCITSPPPWPEAILLGFQHYLVMLGTTVLIPTALVPQMGGGYEE--KAKVI 76

  Fly    88 STMIFVTGIVTYFQATWGVRLPIVQGGTISFLVPTLAILALPQWKCPEQAVMDAMDEAEREELWQ 152
            .|::||.||.|..|..:|.|||.|.|.:.:|:..|::|:...::    ....:.:|..||
plant    77 QTILFVAGINTLLQTLFGTRLPAVVGASYTFVPTTISIILSGRF----SDTSNPIDRFER----- 132

  Fly   153 VRMRELSGAIAVSAMVQVILGYTGLVGKILKYVTPLTIVPTVSLVGLTLFEHAAETASKHWGIAV 217
             .||...||:.|::.:|:|||::||...::::::|::.||.|.|||..|:|......:|...|.:
plant   133 -IMRATQGALIVASTLQMILGFSGLWRNVVRFLSPISAVPLVGLVGFGLYEFGFPGVAKCIEIGL 196

  Fly   218 GTTGMLTLFSQIMSNVPVPILAYRKGHGLEIRQFQLFRLFPVLLTIMIMWGLCGILTATDVFPPS 282
            ....:|...||.:.:|      .:.|.       .:|..|.|:..::|:|....:||....:..:
plant   197 PELLILVFVSQYLPHV------IKSGK-------NVFDRFAVIFAVVIVWIYAHLLTVGGAYNGA 248

  Fly   283 HPS-----RTDVRLNVLTSAKWFYVPYPGQFGWPSVTLSGVLGMLAGVLACTVESLSYYPTVSQM 342
            .|:     ||| |..::.:|.|..||:|.|:|.||........|:.......|||...:..||:.
plant   249 APTTQTSCRTD-RAGIIGAAPWIRVPWPFQWGAPSFDAGEAFAMMMASFVALVESTGAFVAVSRY 312

  Fly   343 SGAHSPPLHAINRGIGTEGFGTVLAGLWGAGNGTNTFGENVGAIGVTKIGSRRVIQWAALIMVLQ 407
            :.|...|...::||||.:|...:::||:|.|.|::...||.|.:.:|::|||||:|.||..|:..
plant   313 ASATMLPPSILSRGIGWQGVAILISGLFGTGAGSSVSVENAGLLALTRVGSRRVVQIAAGFMIFF 377

  Fly   408 GVIGKFGAIFILIPDSVVGGIFCVMFGMIIAFGLSTLQYVDLRSARNLYILGLSIFFPMVLCRWM 472
            .::|||||:|..||..::..::|:.|..:.|.|||.||:.:|.|.|..:|||.|:|..:.:.::.
plant   378 SILGKFGAVFASIPAPIIAALYCLFFAYVGAGGLSFLQFCNLNSFRTKFILGFSVFLGLSIPQYF 442

  Fly   473 Q-----KNPGAIDTGNKTVDSTLSVLLGTTILVGGVLGCLLDNII----PGTPEERGLIDW 524
            .     |..|.:.||.:..:..::|...:...|.|.:...|||.:    ....::||...|
plant   443 NEYTAIKGYGPVHTGARWFNDMVNVPFSSEPFVAGSVAFFLDNTLHKKDSSIRKDRGKHWW 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6293	NP_001262459.1	HCO3_cotransp	32..519	CDD:304903	155/503 (31%)
CG6293	NP_001262459.1	Xan_ur_permease	48..464	CDD:279232	137/420 (33%)
AT5G62890	NP_001032127.2	Xan_ur_permease	37..442	CDD:419983	138/430 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	262	1.000	Domainoid score	I473
eggNOG	1	0.900	-	-		E1_COG2233
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	291	1.000	Inparanoid score	I827
OMA	1	1.010	-	-		QHG61611
OrthoDB	1	1.010	-	-		D387031at2759
OrthoFinder	1	1.000	-	-		FOG0000230
OrthoInspector	1	1.000	-	-		otm2430
orthoMCL	1	0.900	-	-		OOG6_100583
Panther	1	1.100	-	-	O	PTHR11119
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X261
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840