DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6293 and AT4G38050

DIOPT Version :9

Sequence 1:	NP_001262459.1	Gene:	CG6293 / 41259	FlyBaseID:	FBgn0037807	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_195518.2	Gene:	AT4G38050 / 829961	AraportID:	AT4G38050	Length:	709	Species:	Arabidopsis thaliana

Alignment Length:	600	Identity:	174/600 - (28%)
Similarity:	293/600 - (48%)	Gaps:	92/600 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NNVTIEDATDASKSYSQAAN----------TPPSNEKPKPQLL-YAINDNPPWYLSIFLAFQHYL 57
            |..|.|...:..|......|          :....:.|||.|: :.:.|||.:...|:...||||
plant   133 NEATPETENEGGKINKDLENGFYYPGGGGESSEDGQWPKPILMKFGLRDNPGFVPLIYYGLQHYL 197

  Fly    58 TMIGAIVSIPFILTPALCMSDEDANRGIIISTMIFVTGIVTYFQATWGVRLPIVQGGTISFLVPT 122
            :::|::|.||.::.||:..||:|.  ..:||||:.:||:.|.....:|.|||:|||.:..:|.|.
plant   198 SLVGSLVFIPLVIVPAMDGSDKDT--ASVISTMLLLTGVTTILHCYFGTRLPLVQGSSFVYLAPV 260

  Fly   123 LAILALPQWK-CPEQAVMDAMDEAEREELWQVRMRELSGAIAVSAMVQVILGYTGLVGKILKYVT 186
            |.::...::: ..|....|.             ||||.|||.|.::.|.|||::||:..:|:::.
plant   261 LVVINSEEFRNLTEHKFRDT-------------MRELQGAIIVGSLFQCILGFSGLMSLLLRFIN 312

  Fly   187 PLTIVPTVSLVGLTLFEHAAETASKHWGIAVGTTGMLTLFSQIMSNVPVPILAYRKGHGLEIRQF 251
            |:.:.|||:.|||..|.:....|.....|:|....:|.:|:..:..|.:      .||
plant   313 PVVVAPTVAAVGLAFFSYGFPQAGTCVEISVPLILLLLIFTLYLRGVSL------FGH------- 364

  Fly   252 QLFRLFPVLLTIMIMWGLCGILT---ATD---------------------VFPPSHPSRTDVRLN 292
            :|||::.|.|:.:::|.....||   |.|                     |:...| .|||.. |
plant   365 RLFRIYAVPLSALLIWTYAFFLTVGGAYDYRGCNADIPSSNILIDECKKHVYTMKH-CRTDAS-N 427

  Fly   293 VLTSAKWFYVPYPGQFGWPSVTLSGVLGMLAGVLACTVESLSYYPTVSQMSGAHSPPLHAINRGI 357
            ...:|.|..:|||.|:|:|:..:...:.|:...|..:|:|:..|.:.|.:..|..|....::|||
plant   428 AWRTASWVRIPYPFQWGFPNFHMRTSIIMIFVSLVASVDSVGTYHSASMIVNAKRPTRGIVSRGI 492

  Fly   358 GTEGFGTVLAGLWGAGNGTNTFGENVGAIGVTKIGSRRVIQWAALIMVLQGVIGKFGAIFILIPD 422
            ..|||.::|||:||:|.|:.|..||:..|.:||:.|||.:...|:.:::...:||.|||...||.
plant   493 ALEGFCSLLAGIWGSGTGSTTLTENIHTINITKVASRRALVIGAMFLIVLSFLGKLGAILASIPQ 557

  Fly   423 SVVGGIFCVMFGMIIAFGLSTLQYVDLRSARNLYILGLSIFFPMVLCRWMQK------------- 474
            ::...:.|.::.:.::.|||.|:|....|.||:.|:|:|:|..:.:..:.|:
plant   558 ALAASVLCFIWALTVSLGLSNLRYTQTASFRNITIVGVSLFLGLSIPAYFQQYQPLSSLILPSYY 622

  Fly   475 ------NPGAIDTGNKTVDSTLSVLLGTTILVGGVLGCLLDNIIPGTPEERGLIDW--ANEMPLG 531
                  :.|...||.:.:|..::.:|...::|..:|..:|||.:||:.||||:..|  |.:|.:.
plant   623 IPFGAASSGPFQTGIEQLDFAMNAVLSLNMVVTFLLAFILDNTVPGSKEERGVYVWTRAEDMQMD 687

  Fly   532 DDNVNDGTATDYDFP 546
            .:     ...||..|
plant   688 PE-----MRADYSLP 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6293	NP_001262459.1	HCO3_cotransp	32..519	CDD:304903	159/531 (30%)
CG6293	NP_001262459.1	Xan_ur_permease	48..464	CDD:279232	138/440 (31%)
AT4G38050	NP_195518.2	Xan_ur_permease	188..607	CDD:390063	139/448 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	262	1.000	Domainoid score	I473
eggNOG	1	0.900	-	-		E1_COG2233
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	291	1.000	Inparanoid score	I827
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D387031at2759
OrthoFinder	1	1.000	-	-		FOG0000230
OrthoInspector	1	1.000	-	-		otm2430
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11119
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X261
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.930