DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6293 and AT2G05760

DIOPT Version :9

Sequence 1:	NP_001262459.1	Gene:	CG6293 / 41259	FlyBaseID:	FBgn0037807	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_178636.1	Gene:	AT2G05760 / 815127	AraportID:	AT2G05760	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	559	Identity:	183/559 - (32%)
Similarity:	294/559 - (52%)	Gaps:	62/559 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PPSNEKPKPQLLYAINDNPPWYLSIFLAFQHYLTMIGAIVSIPFILTPALCMSDEDANRGIIIST 89
            ||..:  ...|.|.|:.||||..::.||||:|:.|:|....||.:|.||  |...|.:|..:|.|
plant     7 PPMEQ--LQDLEYCIDSNPPWPETVLLAFQNYILMLGTSAFIPALLVPA--MGGSDGDRARVIQT 67

  Fly    90 MIFVTGIVTYFQATWGVRLPIVQGGTISFLVPTLAILALPQWKCPEQAVMDAMDEAEREELWQVR 154
            ::||.||.|..||.:|.|||.|.||:::::||...|:       .:.::....::.||   :...
plant    68 LLFVAGIKTLLQALFGTRLPAVVGGSLAYVVPIAYII-------NDSSLQKISNDHER---FIHT 122

  Fly   155 MRELSGAIAVSAMVQVILGYTGLVGKILKYVTPLTIVPTVSLVGLTLFEHAAETASKHWGIAVGT 219
            ||.:.||:.|::.:|:||||:.:.|...::.:||.:.|.|.||||.:|:.
plant   123 MRAIQGALIVASSIQIILGYSQVWGLFSRFFSPLGMAPVVGLVGLGMFQR--------------- 172

  Fly   220 TGMLTLFSQIMSNVPVPILA-----YRKGHGLEIRQFQLFRLFPVLLTIMIMWGLCGILTATDVF 279
             |...|.:.|...:|:.:|.     |.| |....:...:|..||:|:.:.|:|....||||:..:
plant   173 -GFPQLGNCIEIGLPMLLLVIGLTQYLK-HVRPFKDVPIFERFPILICVTIVWIYAVILTASGAY 235

  Fly   280 --PPS---HPSRTDVRLNVLTSAKWFYVPYPGQFGWPSVTLSGVLGMLAGVLACTVESLSYYPTV 339
              .||   |..||| :.|::::|.||..|||.|:|.|:.::.....|::.||...|||...|...
plant   236 RGKPSLTQHSCRTD-KANLISTAPWFKFPYPLQWGPPTFSVGHSFAMMSAVLVSMVESTGAYIAA 299

  Fly   340 SQMSGAHSPPLHAINRGIGTEGFGTVLAGLWGAGNGTNTFGENVGAIGVTKIGSRRVIQWAALIM 404
            |:::.|..||.:.::||||.:|.|.:|.||:|.|.|:....||||.:|:|::|||||:|.:|..|
plant   300 SRLAIATPPPAYVLSRGIGWQGIGVLLDGLFGTGTGSTVLVENVGLLGLTRVGSRRVVQVSAGFM 364

  Fly   405 VLQGVIGKFGAIFILIPDSVVGGIFCVMFGMIIAFGLSTLQYVDLRSARNLYILGLSIF----FP 465
            ::...:|||||:|..||..:...:.|::||::.|.|||.||:.::.|.|||.|.|||:|    .|
plant   365 IVFSTLGKFGAVFASIPVPIYAALHCILFGLVAAVGLSFLQFTNMNSMRNLMITGLSLFLGISIP 429

  Fly   466 MVLCR-WMQKNPGAIDTGNKTVDSTLSVLLGTTILVGGVLGCLLDNI--IPGTPEERGLIDWANE 527
            ....: |..::.|.:.|.....::.|:.|..:...||.::...:||.  :..:.::||:..|...
plant   430 QFFAQYWDARHYGLVHTNAGWFNAFLNTLFMSPATVGLIIAVFMDNTMEVERSKKDRGMPWWVKF 494

  Fly   528 MPLGDDNVNDGTATDYDFPLGMDAIRRWKWTYYIPFMPT 566
            .....||.|:   ..|..|..::..          |.||
plant   495 RTFRGDNRNE---EFYTLPFNLNRF----------FPPT 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6293	NP_001262459.1	HCO3_cotransp	32..519	CDD:304903	170/503 (34%)
CG6293	NP_001262459.1	Xan_ur_permease	48..464	CDD:279232	153/429 (36%)
AT2G05760	NP_178636.1	Xan_ur_permease	26..433	CDD:419983	154/436 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	262	1.000	Domainoid score	I473
eggNOG	1	0.900	-	-		E1_COG2233
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	291	1.000	Inparanoid score	I827
OMA	1	1.010	-	-		QHG61611
OrthoDB	1	1.010	-	-		D387031at2759
OrthoFinder	1	1.000	-	-		FOG0000230
OrthoInspector	1	1.000	-	-		otm2430
orthoMCL	1	0.900	-	-		OOG6_100583
Panther	1	1.100	-	-	LDO	PTHR11119
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X261
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840