Protein Alignment CG6293 and Slc23a4

DIOPT Version :9

• Sequence 1: NP_001262459.1
• Gene: CG6293 / 41259
• FlyBaseID: FBgn0037807
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: XP_006506197.1
• Gene: Slc23a4 / 243753
• MGIID: 1917272
• Length: 615
• Species: Mus musculus
• Alignment Length: 554
• Identity: 252/554 - (45%)
• Similarity: 354/554 - (63%)
• Gaps: 23/554 - (4%)

  Fly    25 PPSNEKPKPQLLYAINDNPPWYLSIFLAFQHYLTMIGAIVSIPFILTPALCMSDEDANRGIIIST 89
            |.||.    .|.|.|.|:|||||.|||..||:||.:|.:|::|.||...||:..:...:..:|||
Mouse    38 PNSNS----NLAYGILDSPPWYLCIFLGIQHFLTALGGLVAVPLILAKDLCLQHDPLTQSYLIST 98

  Fly    90 MIFVTGIVTYFQATWGVRLPIVQGGTISFLVPTLAILALPQWKCPE---QAVMDAMDEAEREELW 151
            :.||:||.|..|...||||||:||||.:|:.|:||:|:||.|||||   .|........|..|.|
Mouse    99 IFFVSGICTLLQVFLGVRLPILQGGTFAFVAPSLAMLSLPAWKCPEWTLNASQVNTSSPEFIEEW 163

  Fly   152 QVRMRELSGAIAVSAMVQVILGYTGLVGKILKYVTPLTIVPTVSLVGLTLFEHAAETASKHWGIA 216
            |.|:|||.|||.|::.||:::|::||:|.:::::.||||.||:|||.|.||:.|...|..||||:
Mouse   164 QKRIRELQGAIMVASCVQMLVGFSGLIGFLMRFIGPLTIAPTISLVALPLFDSAGSDAGIHWGIS 228

  Fly   217 VGTTGMLTLFSQIMSNVPVPILAYRKGHGLEIRQFQLFRLFPVLLTIMIMWGLCGILTATDVFPP 281
            ..|..::.||||.:.||.||:..|.:.....|.:|.||::|||||.:.:.|..|.:||.|:..|.
Mouse   229 ALTIFLIVLFSQYLKNVMVPVPVYGRRKKCHISRFNLFQVFPVLLALCLSWLFCFVLTVTNTLPE 293

  Fly   282 S-----HPSRTDVRLNVLTSAKWFYVPYPGQFGWPSVTLSGVLGMLAGVLACTVESLSYYPTVSQ 341
            |     :.:|||.:.:||:.|.||..|||||:|.|:::|:||.|::|||::..|||:..|...::
Mouse   294 SPTAYGYMARTDTKGSVLSQAPWFRFPYPGQWGLPTISLAGVFGIIAGVISSMVESVGDYHACAR 358

  Fly   342 MSGAHSPPLHAINRGIGTEGFGTVLAGLWGAGNGTNTFGENVGAIGVTKIGSRRVIQWAALIMVL 406
            :.||..||.||||||||.||.|.:|||.||.||||.::.|||||:|:|::|||.||..|..::::
Mouse   359 LVGAPPPPKHAINRGIGIEGLGCLLAGAWGTGNGTTSYSENVGALGITRVGSRMVIVAAGCVLLV 423

  Fly   407 QGVIGKFGAIFILIPDSVVGGIFCVMFGMIIAFGLSTLQYVDLRSARNLYILGLSIFFPMVLCRW 471
            .|:.||.||.|..||..|:||:|.||||:|.|.|:|.|||||:.|:|||::.|.||:..:.:..|
Mouse   424 MGMFGKIGAAFATIPTPVIGGMFLVMFGIISAVGISNLQYVDMNSSRNLFVFGFSIYCGLAIPNW 488

  Fly   472 MQKNPGAIDTGNKTVDSTLSVLLGTTILVGGVLGCLLDNIIPGTPEERGLIDWANEMPLGDDNVN 536
            :.|||..:.||...:|..:.|||.|.:.|||.||.:|||.|||:.|||||:.|:....  |...:
Mouse   489 VNKNPEKLQTGILQLDQVIQVLLTTGMFVGGFLGFVLDNTIPGSLEERGLLAWSKIQE--DSEES 551

  Fly   537 DGTATDYDFPLGMDAIRRWKW-----TYYIPFMP 565
            ...:..|..|.|:..    |:     |..:||.|
Mouse   552 SKVSKVYGLPWGIGT----KFCTSSCTRLLPFWP 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6293	NP_001262459.1	HCO3_cotransp	32..519	CDD:304903	235/494 (48%)
		Xan_ur_permease	48..464	CDD:279232	203/423 (48%)
Slc23a4	XP_006506197.1	Xan_ur_permease	58..488	CDD:366341	203/429 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	422	1.000	Domainoid score	I629
eggNOG	1	0.900	-	-		E1_COG2233
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	505	1.000	Inparanoid score	I1329
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61611
OrthoDB	1	1.010	-	-		D219070at33208
OrthoFinder	1	1.000	-	-		FOG0000230
OrthoInspector	1	1.000	-	-		otm43403
orthoMCL	1	0.900	-	-		OOG6_100583
Panther	1	1.100	-	-	O	PTHR11119
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1881
SonicParanoid	1	1.000	-	-		X261
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.910