DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6293 and T07G12.5

DIOPT Version :9

Sequence 1:	NP_001262459.1	Gene:	CG6293 / 41259	FlyBaseID:	FBgn0037807	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_501947.1	Gene:	T07G12.5 / 177946	WormBaseID:	WBGene00011596	Length:	555	Species:	Caenorhabditis elegans

Alignment Length:	545	Identity:	184/545 - (33%)
Similarity:	286/545 - (52%)	Gaps:	35/545 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LLYAIND--NPPWYLSIFL-AFQHYLTMIGAIVSIPFILTPALCMSDEDANRGIIISTMIFVT-G 95
            |.:.:|:  :||   ||.| ..|..:..:.:::.||::::..||..|:.....:.:.:..||| |
Worm     4 LHFHVNEIPSPP---SIMLFGLQQMMICLSSLLVIPYVVSDMLCAGDQAMEIRVQLISATFVTSG 65

  Fly    96 IVTYFQATWGVRLPIVQGGTISFLVPTLAILALPQWKCPEQAVMDAMDEAEREELWQVRMRELSG 160
            |.|..|.|:|:||.|:.|.:.:|| |.|...   |...|..|..|..:       ||.:|:.:||
Worm    66 IATILQTTFGMRLSILHGPSFAFL-PALHTF---QATFPCDANTDTSN-------WQEKMQMISG 119

  Fly   161 AIAVSAMVQVILGYTGLVGKILKYVTPLTIVPTVSLVGLTLFEHAAETASKHWGIAVGTTGMLTL 225
            :..::.::..|||:|||||||.||:.|:||||.:||:.:..........:.|| |::.....|.|
Worm   120 SCLIAVLIMPILGFTGLVGKISKYIGPVTIVPIMSLLTIGTVPDIESKMALHW-ISIVEFLTLIL 183

  Fly   226 FSQIMS--NVPVPILAYRKGHGLEIRQFQLFRLFPVLLTIMIMWGLCGILTATDVFPPSHPSRTD 288
            |..|:.  .||:||.:..:......|| ::|..||.||.|.|:|.:|.|:|.|:..|....:|||
Worm   184 FVVILERYEVPIPIFSLSEKKFKFTRQ-KIFSQFPYLLGISIVWFICFIMTITNAEPRGGEARTD 247

  Fly   289 --VRLNVLTSAKWFYVPYPGQFGWPSVTLSGVLGMLAGVLACTVESLSYYPTVSQMSGAHSPPLH 351
              ..:.|.....|..:|.|..||.|...|:.|.|..|...|..:||:..|...:::|....||..
Worm   248 QNASITVFDQTPWVQMPMPLFFGPPKFNLALVCGFTASCFAAMIESIGDYNLCAKISKQSRPPPS 312

  Fly   352 AINRGIGTEGFGTVLAGLWGAGNGTNTFGENVGAIGVTKIGSRRVIQWAALIMVLQGVIGKFGAI 416
            ..||....||.|.:||.|||.|.|..|:.||:..:.|||:.||..:|.|.:.::|.|||.||.|.
Worm   313 NTNRAFVVEGIGCILAALWGVGTGVTTYAENIAIMSVTKVTSRITMQMAGVFLILAGVISKFAAF 377

  Fly   417 FILIPDSVVGGIFCVMFGMIIAFGLSTLQYVDLRSARNLYILGLSIFFPMVLCRWMQKNPGAIDT 481
            ..:||:.::||:..:...:|....||.||.||::.:|||.|:|:||...:.:....:|.|  ::|
Worm   378 LSMIPEPIIGGLLAMGVCLINGVSLSNLQTVDMKLSRNLTIIGVSIIMGLTVATHFEKTP--LNT 440

  Fly   482 GNKTVDSTLSVLLGTTILVGGVLGCLLDNIIPG-TPEERGLIDWANEMPLGDDNVNDGTATD--- 542
            ||:.||.....||...:|:|||:..:||||..| |..:||.:...:|    ||:|.:....:
Worm   441 GNQIVDDVFGTLLTIRMLIGGVIAFVLDNITGGATRRQRGFVSEIDE----DDDVEEQATVEMNG 501

  Fly   543 YDFPLGMDA-IRRWKWTYYIPFMPT 566
            |..|..::. ..|:.|..|:|.:|:
Worm   502 YALPSKLNQFFLRYSWLTYLPVIPS 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6293	NP_001262459.1	HCO3_cotransp	32..519	CDD:304903	171/492 (35%)
CG6293	NP_001262459.1	Xan_ur_permease	48..464	CDD:279232	148/421 (35%)
T07G12.5	NP_501947.1	Xan_ur_permease	15..435	CDD:279232	149/435 (34%)
T07G12.5	NP_501947.1	HCO3_cotransp	56..432	CDD:304903	139/388 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	242	1.000	Domainoid score	I1235
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H112955
Inparanoid	1	1.050	287	1.000	Inparanoid score	I1711
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61611
OrthoDB	1	1.010	-	-		D219070at33208
OrthoFinder	1	1.000	-	-		FOG0000230
OrthoInspector	1	1.000	-	-		otm14321
orthoMCL	1	0.900	-	-		OOG6_100583
Panther	1	1.100	-	-	O	PTHR11119
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1881
SonicParanoid	1	1.000	-	-		X261
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	14.010