DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6293 and LOC100486632

DIOPT Version :9

Sequence 1:	NP_001262459.1	Gene:	CG6293 / 41259	FlyBaseID:	FBgn0037807	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	XP_002937113.2	Gene:	LOC100486632 / 100486632	-ID:	-	Length:	601	Species:	Xenopus tropicalis

Alignment Length:	557	Identity:	275/557 - (49%)
Similarity:	382/557 - (68%)	Gaps:	18/557 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NEKPKPQ-----LLYAINDNPPWYLSIFLAFQHYLTMIGAIVSIPFILTPALCMSDEDANRGIII 87
            |||.|..     |:|:|:|.|||||.|.||||||:...|.|::||.||...||:..::..:..:|
Frog    46 NEKDKKNSKCITLIYSISDRPPWYLCILLAFQHYILAFGGIIAIPLILAEPLCIKHDNYVKSQLI 110

  Fly    88 STMIFVTGIVTYFQATWGVRLPIVQGGTISFLVPTLAILALPQWKCP--EQAVMD--AMDEAERE 148
            .|:.||:||.|..|.|.|.||||:||||.|.:.||||||:||:||||  |..:.:  |.:.....
Frog   111 CTIFFVSGICTLLQTTIGTRLPILQGGTFSLITPTLAILSLPKWKCPNNEDNIYNGTANNSETDP 175

  Fly   149 ELWQVRMRELSGAIAVSAMVQVILGYTGLVGKILKYVTPLTIVPTVSLVGLTLFEHAAETASKHW 213
            :.|::||||:.||:.|::.:||:||::||:|.:|:::.||.|.||::|:||:||..|.:....||
Frog   176 DTWKLRMREIQGAVIVASTMQVLLGFSGLIGFLLRFLGPLAITPTITLIGLSLFGEAGKKCGVHW 240

  Fly   214 GIAVGTTGMLTLFSQIMSNVPVPILAYRKGHGLEIRQFQLFRLFPVLLTIMIMWGLCGILTATDV 278
            |||..|..::.:|||.:.|:..||:.|.||. ....::.:|:|.||||.:.:.|.:|.:||..:|
Frog   241 GIAALTIALIVIFSQYLVNIECPIIRYSKGK-WNFTKYPIFKLIPVLLGMCLSWLICYLLTHFNV 304

  Fly   279 FPPSHPS-----RTDVRLNVLTSAKWFYVPYPGQFGWPSVTLSGVLGMLAGVLACTVESLSYYPT 338
            ||.:..|     |||:.::.:|:|.||:||||||:|||:|:||.||||||||||.||||:..|.|
Frog   305 FPSNQTSYGYAARTDLDIDAITNAPWFHVPYPGQWGWPTVSLSSVLGMLAGVLASTVESIGDYYT 369

  Fly   339 VSQMSGAHSPPLHAINRGIGTEGFGTVLAGLWGAGNGTNTFGENVGAIGVTKIGSRRVIQWAALI 403
            .|::|||..||.||||||||.||.|.:||||||.||||.::.:|:.|:|:||:|||.|:|.|.::
Frog   370 CSRLSGAPLPPTHAINRGIGIEGIGCILAGLWGTGNGTTSYSQNIAALGITKVGSRLVMQTAGIL 434

  Fly   404 MVLQGVIGKFGAIFILIPDSVVGGIFCVMFGMIIAFGLSTLQYVDLRSARNLYILGLSIFFPMVL 468
            :::.||.||||||||.||:.|:||:|.||||||.|.|:|.||||||.|:|||:|||.|:|..:|:
Frog   435 LLILGVFGKFGAIFITIPEPVIGGMFMVMFGMIAAVGISNLQYVDLNSSRNLFILGFSMFSGLVI 499

  Fly   469 CRWMQKNPGAIDTGNKTVDSTLSVLLGTTILVGGVLGCLLDNIIPGTPEERGLIDWANEMPLGDD 533
            ..|:.||||.|:||.:.:|..|:|||.|.:.|||..||||||.:||:.||||...|..:|  ..:
Frog   500 PTWLAKNPGFINTGVEELDQALTVLLTTNMFVGGFFGCLLDNTVPGSDEERGTSAWHKQM--HPE 562

  Fly   534 NVNDGTATD-YDFPLGMDAIRRWKWTYYIPFMPTYKL 569
            ..|..|... ||.|.....:||..|:.||||:|.:.:
Frog   563 KTNGSTEQSCYDLPFVSKYLRRLSWSRYIPFLPAFHM 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6293	NP_001262459.1	HCO3_cotransp	32..519	CDD:304903	254/500 (51%)
CG6293	NP_001262459.1	Xan_ur_permease	48..464	CDD:279232	216/424 (51%)
LOC100486632	XP_002937113.2	Xan_ur_permease	72..505	CDD:366341	219/433 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	452	1.000	Domainoid score	I503
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H112955
Inparanoid	1	1.050	559	1.000	Inparanoid score	I1086
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D219070at33208
OrthoFinder	1	1.000	-	-		FOG0000230
OrthoInspector	1	1.000	-	-		otm48547
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X261
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060