Protein Alignment Nuak1 and PTK1

DIOPT Version :9

• Sequence 1: NP_001369005.1
• Gene: Nuak1 / 41256
• FlyBaseID: FBgn0262617
• Length: 2803
• Species: Drosophila melanogaster
• Sequence 2: NP_012723.3
• Gene: PTK1 / 853635
• SGDID: S000001681
• Length: 662
• Species: Saccharomyces cerevisiae
• Alignment Length: 605
• Identity: 145/605 - (23%)
• Similarity: 220/605 - (36%)
• Gaps: 222/605 - (36%)

  Fly    55 GNVKMNNHRKKLRQRFDI--IKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRR 117
            |:.::...|.|.|:: |:  :|||..         |..||.:    |..|:|..|     ..|.:
Yeast   206 GSCEVRKIRSKYRKK-DVFALKKLNM---------IYNETPE----KFYKRCSKE-----FIIAK 251

  Fly   118 EVQIMSSVHHPNIIHIY-------EVFENREKMVLVMEFAAGGELYDYLSE---RKVLTEEEARR 172
            ::.     ||.:|.:.:       .|:..| ....|||... .:|:..:.:   |.|...|:. .
Yeast   252 QLS-----HHVHITNTFLLVKVPTTVYTTR-GWGFVMELGL-RDLFAMIQKSGWRSVALAEKF-C 308

  Fly   173 IFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVF-DDQRLLGT-------FCG 229
            ||:|||..|.:||...|.|||||.||:||...|..|:.|||:|:.: .|...|.:       ..|
Yeast   309 IFKQVACGVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIG 373

  Fly   230 SPLYASPEIV-----------EGTPYQGPEVDCWSLGVLLYTLVYGSMPFDGS------------ 271
            ||.||.||::           ...||....:||:.||::|.|||...:||..|
Yeast   374 SPPYAPPEVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNNVIPFLESCSFDTGFRDYCD 438

  Fly   272 ---NFKRLVKQI--SQGDY-------------YEPRKPSRASTLIRDMLTVCPR--KRASIEQIC 316
               ||.||..:.  ::|:|             ::....||.:..:.|     |.  .|.:|:.:.
Yeast   439 AYENFIRLHDRAFRNRGNYRPGPGMEYHLARNFKNGHASRVAWRLAD-----PEAATRYTIDDLF 498

  Fly   317 SHWW-------VNENDNVSC-LDLAEDLANQTPVRLDVLLSLTPATITADQLVVPSAEGAAAAKA 373
            ...|       |:.||...| ..:.:....:.|....:...:...|.|::..:
Yeast   499 EDPWFQGIETCVDANDKYVCKKPIIKTTTYENPRGFHIATDVAATTPTSNPFL------------ 551

  Fly   374 AANERVPRSHSVGSIRDMGPPNTEAERRILDMVAAGGEAALMPSPTRTITPAQSPVQTKRKLQPT 438
              ..|||       ||.|           :|:.|       .||||.|:..:..|       .|.
Yeast   552 --KNRVP-------IRSM-----------VDIAA-------HPSPTATVLASSPP-------PPP 582

  Fly   439 VSTENAAGTTAKKKEKPANSSFVISKDGAPLTEAPPTIIEPQ-ATLMEAETIANIPEEVPVPSYS 502
            .:|           ..||.:.|.       |.|.||    || |||       .:.||.|
Yeast   583 PAT-----------HVPAEALFT-------LRETPP----PQLATL-------TLSEEPP----- 613

  Fly   503 QKDMQAVGDICDLLMGTATTPAPAPPAPTPVARQPTRGKLDAVVETPEEKDATKVIKKFVNKHKT 567
                              .||||:.|: .|.||  .||      .:|.     :|:      |..
Yeast   614 ------------------ATPAPSAPS-APSAR--VRG------HSPH-----RVV------HHH 640

  Fly   568 ADLVNAINESASKAAAPVSA 587
            .::||::..|:|.|::.|.|
Yeast   641 LNIVNSLVHSSSAASSQVPA 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nuak1	NP_001369005.1	STKc_NUAK	68..321	CDD:270975	83/322 (26%)
PTK1	NP_012723.3	PKc_like	202..503	CDD:419665	86/328 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345259
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840