Protein Alignment Nuak1 and VHS1

DIOPT Version :9

• Sequence 1: NP_001369005.1
• Gene: Nuak1 / 41256
• FlyBaseID: FBgn0262617
• Length: 2803
• Species: Drosophila melanogaster
• Sequence 2: NP_010533.1
• Gene: VHS1 / 851834
• SGDID: S000002655
• Length: 461
• Species: Saccharomyces cerevisiae
• Alignment Length: 413
• Identity: 90/413 - (21%)
• Similarity: 157/413 - (38%)
• Gaps: 127/413 - (30%)

  Fly    56 NVKMNNHRKKLRQRFDIIKKLGQGTYGKVQLGINKETGQEVAIK-TIKKCKIEAEADL------- 112
            |.::||:.        |..::|:|.||.|...::..|.::.||| .::...:..|||:
Yeast     6 NCRINNYL--------ITSQIGEGAYGLVYRALDIRTDRQYAIKAVVQSYGVSKEADMGNDKIHK 62

  Fly   113 -------------------VRI---------------------RREVQIMSSV-HHPNIIHIYEV 136
                               ||:                     .:|:.:...| ||.||:.|:||
Yeast    63 NSVKLQKKLAKLFKESKNVVRVPSIDLESIENMSEEDFKKLPHYKEISLHLRVHHHKNIVTIHEV 127

  Fly   137 FENREKMVLVMEFAAGGELYDYLSERKVLTEE-EARRIFRQVATAVYYCHKHKICHRDLKLENIL 200
            .::.....:||::.........:..|..:|.. ..:::|.|:.:|:.|||:|.|.|.|:|.||:|
Yeast   128 LQSAVCTFIVMDYYPTDLFTSIVDNRHFVTNGLLVKKVFLQICSALNYCHEHGIYHCDIKPENLL 192

  Fly   201 LDEKGNAKIADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGP------------------ 247
            ||.:.|..:.|||||.             :..|..|.:..|:.|..|
Yeast   193 LDTEDNVFLCDFGLST-------------TSTYIKPNVCIGSSYYMPPERISFDGRVSSSKSGGH 244

  Fly   248 ---------EVDCWSLGVLLYTLVYGSMPF-------DGSNF-----KRLVKQI--SQGDYYEPR 289
                     ..|.||||::|..|.....|:       |.:.:     ..::|||  ...|:|
Yeast   245 KLGKVCPSCNGDLWSLGIILINLTCIRNPWLKADKTEDNTYYYFTKDPNILKQILPLSDDFY--- 306

  Fly   290 KPSRASTLIRDMLTVCPRKRASIEQICSHWWVNENDNVSCLDLAEDLANQTPVRLDVLLS-LTPA 353
                  :|:..:|.|.|:.|.|::::     :.|..:::.......|:...|:...|... ::|.
Yeast   307 ------SLLSKILQVNPKNRMSLQEL-----MKEVSSITSFTNEGPLSKVPPLSKSVYEKFVSPV 360

  Fly   354 TITADQLVVPSAEGAAAAKAAAN 376
            ..|.:.|...|......:|||.|
Yeast   361 DNTNENLSPKSYVYMHDSKAAKN 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nuak1	NP_001369005.1	STKc_NUAK	68..321	CDD:270975	75/343 (22%)
VHS1	NP_010533.1	STKc_Pat1_like	11..330	CDD:270895	76/353 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345261
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930