Protein Alignment Nuak and TSSK6

DIOPT Version :10

• Sequence 1: NP_001369005.1
• Gene: Nuak / 41256
• FlyBaseID: FBgn0262617
• Length: 2803
• Species: Drosophila melanogaster
• Sequence 2: NP_114426.1
• Gene: TSSK6 / 83983
• HGNCID: 30410
• Length: 273
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 96/263 - (36%)
• Similarity: 146/263 - (55%)
• Gaps: 16/263 - (6%)

  Fly    74 KKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVR--IRREVQIMSSVHHPNIIHIYEV 136
            :.:|:|:|.||::..:|:....||||.:.:.:  |..|.|.  :.||:.|:..|.||:|:|::|.
Human    16 RTIGEGSYSKVKVATSKKYKGTVAIKVVDRRR--APPDFVNKFLPRELSILRGVRHPHIVHVFEF 78

  Fly   137 FE-NREKMVLVMEFAAGGELYDYLSERKVLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENIL 200
            .| ...|:.:||| ||..:|...:.....:...:||.:|.|:|.||.|.|.|.:.|||||.||:|
Human    79 IEVCNGKLYIVME-AAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVL 142

  Fly   201 L--DEKGNAKIADFGL---SNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVLLYT 260
            |  ||: ..|:.|||.   ::.:.|  |..|:|||..|||||::.|.||...:.|.||:||:||.
Human   143 LSPDER-RVKLTDFGFGRQAHGYPD--LSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYV 204

  Fly   261 LVYGSMPFDGSNFKRLVKQISQGDYYEP--RKPSRASTLIRDMLTVCPRKRASIEQICSHWWVNE 323
            :|.|.||||.|:...|.::..:|..|..  ....|...||.::|...|..|.|..|:..:.|:..
Human   205 MVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWLRA 269

  Fly   324 NDN 326
            .|:
Human   270 GDS 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nuak	NP_001369005.1	STKc_NUAK	68..321	CDD:270975	94/256 (37%)
TSSK6	NP_114426.1	STKc_TSSK6-like	11..267	CDD:271066	94/256 (37%)