Protein Alignment Nuak and Tssk5

DIOPT Version :10

• Sequence 1: NP_001369005.1
• Gene: Nuak / 41256
• FlyBaseID: FBgn0262617
• Length: 2803
• Species: Drosophila melanogaster
• Sequence 2: NP_898922.2
• Gene: Tssk5 / 73542
• MGIID: 1920792
• Length: 372
• Species: Mus musculus
• Alignment Length: 351
• Identity: 109/351 - (31%)
• Similarity: 169/351 - (48%)
• Gaps: 70/351 - (19%)

  Fly    74 KKLGQGTYGKVQLGI--------NKETGQE--------VAIKTIKKCKIEAEADLVRIRREVQIM 122
            ||:|.|.:.||.|..        |.....:        ||||.:...:..||.....:.||:..:
Mouse    31 KKIGSGAFSKVYLAYATRERMKHNPRLSSDLRGKRHTMVAIKIVSMAEAPAEYSRKFLPREILSL 95

  Fly   123 SSVH-HPNIIHIYEVFENREKMVLVMEFAAGGELYDYL---SERKV---LTEEEARRIFRQVATA 180
            ::.: |.||:.:||.::|.::..||:|.||.|:|.:::   |:.:.   |.||||||:|.|:.:|
Mouse    96 NATYKHMNIVQLYETYQNSQRSYLVLELAARGDLLEHINAVSDLRCCPGLEEEEARRLFWQLVSA 160

  Fly   181 VYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSN-VFDDQRLLGTFCGSPLYASPEIVEGTPY 244
            |.:||...|.|||||.||||||::|..|:.|||.:| |.....||.|||||..|.:|||:....|
Mouse   161 VAHCHNVGIVHRDLKCENILLDDQGFIKLTDFGFANWVGLKNSLLSTFCGSVAYTAPEILMSKKY 225

  Fly   245 QGPEVDCWSLGVLLYTLVYGSMPFDGSNFKRLVKQISQGDYYEPRKPSRASTLIRDMLTVCPRKR 309
            .|.:.|.||||::|:.:|.|.:||......|::..|.:|..:.|........|||.:|.:.|.:|
Mouse   226 NGEQADLWSLGIILHAMVSGKLPFKEHQPHRMLNLIRRGPIFRPGLSPECRDLIRGLLQLHPCER 290

  Fly   310 ASIEQICSHWWVNENDNVSCLDLAEDLANQTPVRLDVLLSLTPATITADQLVVPSAEGAAAAKAA 374
            ..::|:.:|.|                                        ::|:....::|..|
Mouse   291 LDLQQVAAHCW----------------------------------------MLPAEHMLSSALGA 315

  Fly   375 ANERVPRSHSVGSIRDMGPPNTEAER 400
            ..|   :.||..::   .|.|||.:|
Mouse   316 PRE---QDHSWSTV---APDNTEPDR 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nuak	NP_001369005.1	STKc_NUAK	68..321	CDD:270975	97/270 (36%)
Tssk5	NP_898922.2	Protein Kinases, catalytic domain	26..301	CDD:473864	97/269 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	314..372		9/28 (32%)