Protein Alignment Nuak1 and CG8485

DIOPT Version :9

• Sequence 1: NP_001369005.1
• Gene: Nuak1 / 41256
• FlyBaseID: FBgn0262617
• Length: 2803
• Species: Drosophila melanogaster
• Sequence 2: NP_610942.2
• Gene: CG8485 / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Alignment Length: 870
• Identity: 225/870 - (25%)
• Similarity: 345/870 - (39%)
• Gaps: 192/870 - (22%)

  Fly    65 KLRQRFDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPN 129
            |:...:|:.:.||.|.:..|:|..:..||.:||:|.:.|.|:: :.....:.:||:.|..|.|||
  Fly    15 KIAGLYDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKLD-DVSKAHLFQEVRCMKLVQHPN 78

  Fly   130 IIHIYEVFENREKMVLVMEFAAGGELYDYLSER-KVLTEEEARRIFRQVATAVYYCHKHKICHRD 193
            ::.:|||.:.:.|:.||:|...||:||||:.:. ..|:||.||:.|||:..|:.|||:..:.|||
  Fly    79 VVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAITYCHQLHVVHRD 143

  Fly   194 LKLENILLDEK-GNAKIADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVL 257
            ||.||::..|| |..|:.|||.||.|...:.|.|||||..|::|||:.|..|..|.||.|||||:
  Fly   144 LKPENVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSYDAPAVDIWSLGVI 208

  Fly   258 LYTLVYGSMPFDGSNFKRLVKQISQGDYYEPRKPSRAST----LIRDMLTVCPRKRASIEQICSH 318
            ||.||.|..||:.:|....:..|....|   ..||..||    ||..||...|:|||::|:|.|.
  Fly   209 LYMLVCGQAPFEKANDSETLTMIMDCKY---TVPSHVSTDCRDLIASMLVRDPKKRATVEEIASS 270

  Fly   319 WW---VNENDN-----------VSCLDLAED---------LANQTPVRLDVLLSLTPAT---ITA 357
            .|   ::|.|:           ||...|.|:         :......:.::|.:|....   |||
  Fly   271 AWLKPIDEPDSTTSTSEHFLPLVSREQLGEEDHAFIIQKMINGNIASKEEILQALDKNKYNHITA 335

  Fly   358 DQLVVPSAE----------------------GAAAAKAAANERVPRSHSVGSI------------ 388
            ...::....                      |.|:.|....:..|.....|.:
  Fly   336 TYFLLAELRLRRRREELAQKQRLLNDASMKVGDASRKLVPEKPSPTEAQKGGVPISINVTPAAQF 400

  Fly   389 -RDMGPPN-----------TEAERRILDMVAAGGEAALMPSPTRTITPAQSPVQTKRKLQPTVST 441
             .|.|.|:           .:.|....:..|.|.|..:..|..|   .|.|.....|.:....|:
  Fly   401 ANDGGKPDKRSRKCSIVREEDEEESATECTAVGNELKVTSSSRR---EAFSDSPFSRSIHERSSS 462

  Fly   442 ENAAGTTAKKKEKPANSSFVISKDGAPLTEAPPTIIEPQAT----LMEAETIANIPEEVPVPSYS 502
            |....|   |.|:.|||       |.|.......::...||    |.:.|..|.|.|:
  Fly   463 EPGNQT---KGEQIANS-------GVPSHSRTKIVVSVDATLAHKLKQMEKSAKIDED------- 510

  Fly   503 QKDMQAVGDICDLLMGTATTPAPAPPAPTPVARQPTRGKLDAVVETPE------EKDATKV-IKK 560
                 .:..:.:|.:| ...|.|: .:..||... .|.||:. :.||.      ..|.||. .||
  Fly   511 -----TLSGLKELEIG-KLKPLPS-SSKNPVLTH-RRTKLNK-IRTPSCSSSEASDDDTKTRNKK 566

  Fly   561 FVNKHKTADLVNAINESASKAAAPVSAVAPPPFVRKCSLQDESTLNKFNAERRKSR--ILETAEK 623
            .:||                            ||       ..|..:|...||.|.  ..::.::
  Fly   567 KINK----------------------------FV-------GDTPVRFRMHRRDSHDDSSDSQDQ 596

  Fly   624 FQPPPPVAA-APPEKPKKLSIPGVSVG-SFKKEFEKKATNPPAAEGPTPGELRAQEQVAAAAAAA 686
            ..|||..|: |.....|..|:.|...| |..||...|:.....:......:...::.|...:.|.
  Fly   597 LYPPPGSASNAGNFISKSGSVSGKKEGQSQYKEPNNKSDENRKSHSQKNRKQHNKDHVDKHSHAE 661

  Fly   687 QEAETLSTPPPSPVVAQSLEGSDSKNSV-ASISLDEARRSMENSIALLLQAQNE-------SSKE 743
            ::....||       |.:...::.:..: .|.|||....:.|..:.....|::|       |::.
  Fly   662 RQLADSST-------ATTGNSTNRRRRIRESQSLDRITEAQEYEMRHRCYAESEAASSSSSSTQH 719

  Fly   744 VDQ----LCAQTETIGVSEPATQQERERKLKNARAIIG---NAIQPVIRRPTPF---YGIGNGFG 798
            :||    |...|.|..|:|...:.:.|....||...|.   ||.:..:::...|   ..:...|.
  Fly   720 IDQRYSLLSLNTSTFSVAETKEEYDEEADATNATDQIMNTLNAAKATLQQEQYFNNNTNLSRNFN 784

  Fly   799 NGMGGAV------GASGATVNNAPK 817
            :....::      .|:|...|..||
  Fly   785 HNHNQSIIHISSQKANGKKSNETPK 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nuak1	NP_001369005.1	STKc_NUAK	68..321	CDD:270975	108/261 (41%)
CG8485	NP_610942.2	STKc_SNRK	16..273	CDD:270976	107/260 (41%)
		S_TKc	20..273	CDD:214567	107/256 (42%)
		UBA_SNRK	296..338	CDD:270524	7/41 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461606
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840