DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nuak1 and Tssk6

DIOPT Version :9

Sequence 1:	NP_001369005.1	Gene:	Nuak1 / 41256	FlyBaseID:	FBgn0262617	Length:	2803	Species:	Drosophila melanogaster
Sequence 2:	NP_001099548.1	Gene:	Tssk6 / 290670	RGDID:	1559764	Length:	273	Species:	Rattus norvegicus

Alignment Length:	263	Identity:	97/263 - (36%)
Similarity:	147/263 - (55%)	Gaps:	16/263 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 KKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVR--IRREVQIMSSVHHPNIIHIYEV 136
            :.:|:|:|.||::..:|:....||||.:.:.:  |..|.|.  :.||:.|:..|.||:|:|::|.
  Rat    16 RTIGEGSYSKVKVATSKKYKGTVAIKVVDRRR--APPDFVNKFLPRELSILRGVRHPHIVHVFEF 78

  Fly   137 FE-NREKMVLVMEFAAGGELYDYLSERKVLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENIL 200
            .| ...|:.:||| ||..:|...:.....:...:||.:|.|:|.||.|.|.|.:.|||||.||:|
  Rat    79 IEVCNGKLYIVME-AAATDLLQAVQRNGRIPGSQARELFSQIAGAVRYLHDHHLVHRDLKCENVL 142

  Fly   201 L--DEKGNAKIADFGL---SNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVLLYT 260
            |  ||: ..|:.|||.   ::.:.|  |..|:|||..|||||::.|.||...:.|.|||||:||.
  Rat   143 LSPDER-RVKLTDFGFGRQAHGYPD--LSTTYCGSAAYASPEVLLGIPYDPKKYDVWSLGVVLYV 204

  Fly   261 LVYGSMPFDGSNFKRLVKQISQGDYYEP--RKPSRASTLIRDMLTVCPRKRASIEQICSHWWVNE 323
            :|.|.||||.|:...|.::..:|..|..  ....|..:||.::|...|..|.|..|:..:.|:..
  Rat   205 MVTGCMPFDDSDIAGLPRRQKRGVLYPDGLELSERCKSLIAELLQFSPSARPSAGQVARNGWLRA 269

  Fly   324 NDN 326
            .|:
  Rat   270 GDS 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nuak1	NP_001369005.1	STKc_NUAK	68..321	CDD:270975	95/256 (37%)
Tssk6	NP_001099548.1	STKc_TSSK6-like	11..267	CDD:271066	95/256 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349130
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840