Protein Alignment Nuak and nuak1

DIOPT Version :10

• Sequence 1: NP_001369005.1
• Gene: Nuak / 41256
• FlyBaseID: FBgn0262617
• Length: 2803
• Species: Drosophila melanogaster
• Sequence 2: XP_002931675.2
• Gene: nuak1 / 100491029
• XenbaseID: XB-GENE-980289
• Length: 660
• Species: Xenopus tropicalis
• Alignment Length: 523
• Identity: 217/523 - (41%)
• Similarity: 303/523 - (57%)
• Gaps: 76/523 - (14%)

  Fly    17 GAEAAAP-TGLDATGNSLAHPSGIPQDQIDNIMSGIANTGNVKMNNHRKKLRQRFDIIKKLGQGT 80
            ||:|.:| .||    ....|.|  |.|:.|:....:|....||.::|:..|:.|:::::.||:||
 Frog    10 GADAKSPVVGL----AEQMHLS--PCDEEDDTAGALAKQHGVKRHHHKHNLKHRYELLETLGKGT 68

  Fly    81 YGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNIIHIYEVFENREKMVL 145
            ||||:..|.:.:|:.||||:|:|.||..|.|:|.||||::||||::||:||.|||||||::|:|:
 Frog    69 YGKVKRAIERFSGRVVAIKSIRKDKIRDEQDMVHIRREIEIMSSLNHPHIIRIYEVFENKDKIVI 133

  Fly   146 VMEFAAGGELYDYLSERKVLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIA 210
            :||:|:.||||||:|||:.|:|.|.|..|||:.:||:||||:.:.|||||||||||||.||.|||
 Frog   134 IMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDENGNIKIA 198

  Fly   211 DFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVLLYTLVYGSMPFDGSNFKR 275
            ||||||::...:.|.||||||||||||||.|.||:|||||.|:|||||||||||:|||||.:.|.
 Frog   199 DFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKN 263

  Fly   276 LVKQISQGDYYEPRKPSRASTLIRDMLTVCPRKRASIEQICSHWWVNENDNVSCLDL-------- 332
            |::|||.|:|.||.:||.|..|||.||.|.|.:||:||.|.:|||||.:...|..|.
 Frog   264 LIRQISSGEYREPTQPSDARGLIRWMLMVNPERRATIEDIANHWWVNWSYKSSVCDCDVLRDSES 328

  Fly   333 -------------------AED----LANQTPVRLDVLLSLTPATITADQLVVPSAEGAAAAKAA 374
                               ||:    |:..:.:.|:...||..:...:| :.....:||....:.
 Frog   329 PLLARFIDWHNRSTTRQLEAENKSKCLSKPSEMSLEQQRSLKKSKKESD-IAQSLQDGADETSSV 392

  Fly   375 ANERVP-----------RSHSVGSIRDMGPP------NTEAERRILDMVAAGGEAALMPSPTRTI 422
            ...:.|           ||||.|.|..:..|      ||:.|         .|...|.|:.|:.:
 Frog   393 TTSKRPKGILKKRNGDYRSHSAGYIEGVVSPVLSPTYNTDDE---------NGHIDLSPNSTQDL 448

  Fly   423 -------TPAQSPVQTKRKLQPTVSTENAAGTTAKKKEKPANSSFVISKDGAPLTEAPPTIIEPQ 480
                   |...:|:..|..|:.|...|:...::.::.|    ||.::..||.....:...|.|.:
 Frog   449 EVPIICDTKQATPMPKKGILKKTPQRESGYYSSPERSE----SSELLDNDGEESINSALVISETK 509

  Fly   481 ATL 483
            .|:
 Frog   510 RTV 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nuak	NP_001369005.1	STKc_NUAK	68..321	CDD:270975	158/252 (63%)
nuak1	XP_002931675.2	STKc_NUAK	56..309	CDD:270975	158/252 (63%)