Protein Alignment Sirt6 and sirt6

DIOPT Version :9

• Sequence 1: NP_649990.2
• Gene: Sirt6 / 41254
• FlyBaseID: FBgn0037802
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_989353.1
• Gene: sirt6 / 394980
• XenbaseID: XB-GENE-5929105
• Length: 331
• Species: Xenopus tropicalis
• Alignment Length: 313
• Identity: 155/313 - (49%)
• Similarity: 208/313 - (66%)
• Gaps: 13/313 - (4%)

  Fly     1 MSCNYADGLSAYDNKGILGAPESFDSDEVVAEKCQELAELIKKSGHVVLHTGAGISTSAGIPDFR 65
            ||.|||.|||.|.:||..|.||:||..:.:..|..|||::|:||.:||.|||||||||.||||||
 Frog     1 MSVNYAAGLSPYSDKGRCGLPEAFDPPDELCRKVVELADMIRKSSYVVFHTGAGISTSCGIPDFR 65

  Fly    66 GPKGVWTLEEKGEKPDFNVSFDEARPTKTHMAIIALIESGYVQYVISQNIDGLHLKSGLDRKYLS 130
            ||.|||||||||..|.|:::|:.|.|:.||||::.|...|.:::::|||:||||::||..|:.|:
 Frog    66 GPNGVWTLEEKGVNPKFDITFESACPSPTHMALLQLQRVGILKFLVSQNVDGLHVRSGFPREQLA 130

  Fly   131 ELHGNIYIEQCKKCRRQFVSPSAVETVGQKSLQRACKSSMDSKGRSCRSGILYDNVLDWEHDLPE 195
            |||||:::|:|.||.:|:|....|.|:|.|...|.|........|:|| |.|.|.:||||..||:
 Frog   131 ELHGNMFVEECSKCSKQYVRDQVVGTMGLKPTGRLCDVPKVRGLRACR-GKLKDTILDWEDSLPD 194

  Fly   196 NDLEMGVMHSTVADLNIALGTTLQIVPSGDLPLKNLKCGGKFVICNLQPTKHDKKANLIISSYVD 260
            .||.:.......|||:|.|||:|||.|||:|||...:.|||.||.|||||||||.|:|.|..|||
 Frog   195 RDLNLADEACRKADLSITLGTSLQIRPSGNLPLLTKRKGGKLVIVNLQPTKHDKHADLRIHGYVD 259

  Fly   261 VVLSKVCKLLGVEIPEYSEASDPTKQSKPMEWTIPTSNVNTFHRQYKKYVKDS 313
            .|::::.:|||.:||.::  ..|||       |.||   |..:::...:..||
 Frog   260 EVMTQLMELLGHKIPVWT--GMPTK-------TEPT---NGNYKEENHFYNDS 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt6	NP_649990.2	SIRT7	45..258	CDD:238701	114/212 (54%)
sirt6	NP_989353.1	SIRT7	45..257	CDD:238701	114/212 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	128	1.000	Domainoid score	I5283
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H6924
Inparanoid	1	1.050	295	1.000	Inparanoid score	I2695
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1503290at2759
OrthoFinder	1	1.000	-	-		FOG0006144
OrthoInspector	1	1.000	-	-		oto103467
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4758
SonicParanoid	1	1.000	-	-		X4436
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090