Protein Alignment Sirt6 and Sirt7

DIOPT Version :9

• Sequence 1: NP_649990.2
• Gene: Sirt6 / 41254
• FlyBaseID: FBgn0037802
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: XP_008766699.1
• Gene: Sirt7 / 303745
• RGDID: 1305876
• Length: 426
• Species: Rattus norvegicus
• Alignment Length: 307
• Identity: 107/307 - (34%)
• Similarity: 149/307 - (48%)
• Gaps: 65/307 - (21%)

  Fly    22 ESFDSDEVVAEKCQELAELIKKSGHVVLHTGAGISTSAGIPDFRGPKGVWTLEEKGEKPDFNVSF 86
            |..|..|.:..|.:|||..::.:.|:|::|||||||:|.|||:|||.|||||.:|| :|......
  Rat    78 EVCDDPEELRRKVRELAGAVRSARHLVVYTGAGISTAASIPDYRGPNGVWTLLQKG-RPVSAADL 141

  Fly    87 DEARPTKTHMAIIALIESGYVQYVISQNIDGLHLKSGLDRKYLSELHGNIYIEQCKKCRRQFVSP 151
            .||.||.|||:|..|.:...||:|:|||.|||||:|||.|..:||||||:|||.....|.|.:..
  Rat   142 SEAEPTLTHMSITQLHKHKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVSSAQRTQGLGD 206

  Fly   152 SAVE-TVGQKSLQRACKSSMDSK-------------------GRSC-RSGI-LYDNV-------- 186
            ..:. ||  .||.:.|.|.:.::                   ||:| :.|. |.|.:
  Rat   207 KQMSLTV--PSLPQVCTSCIPNREYVRVFDVTERTALHRHLTGRTCHKCGTQLRDTIVHFGERGT 269

  Fly   187 ----LDWEHDLPENDLEMGVMHSTVADLNIALGTTLQIV-----------PSGDLPLKNLKCGGK 236
                |:|         |.....::.||..:.||::|:::           |....|        |
  Rat   270 LGQPLNW---------EAATEAASKADTILCLGSSLKVLKKYPRLWCMTKPPSRRP--------K 317

  Fly   237 FVICNLQPTKHDKKANLIISSYVDVVLSKVCKLLGVEIPEYSEASDP 283
            ..|.|||.|..|..|.|.:....|.|:..:...||:|||.|:...||
  Rat   318 LYIVNLQWTPKDDWAALKLHGKCDDVMRLLMDELGLEIPVYNRWQDP 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt6	NP_649990.2	SIRT7	45..258	CDD:238701	90/257 (35%)
Sirt7	XP_008766699.1	SIRT7	102..339	CDD:238701	90/256 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D468902at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820