Protein Alignment Sirt6 and Sirt3

DIOPT Version :9

• Sequence 1: NP_649990.2
• Gene: Sirt6 / 41254
• FlyBaseID: FBgn0037802
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: XP_006230588.1
• Gene: Sirt3 / 293615
• RGDID: 1308374
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 275
• Identity: 76/275 - (27%)
• Similarity: 115/275 - (41%)
• Gaps: 60/275 - (21%)

  Fly    35 QELAELI--KKSGHVVLHTGAGISTSAGIPDFRGP-KGVWT------------LEEKG-----EK 79
            |::|||:  :....||:..||||||.:||||||.| .|:::            :.|.|     .|
  Rat    61 QDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPK 125

  Fly    80 PDFNVSFD----EARPTKTHMAIIALIESGYVQYVISQNIDGLHLKSGLDRKYLSELHGNIYIEQ 140
            |.|.::.:    ..||...|..:..|.:...:..:.:||||||...||:....|.|.||:.....
  Rat   126 PFFTLAKELYPGHYRPNVAHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGSFVSAT 190

  Fly   141 CKKCRRQFVSPSAVETVGQKSLQR--ACKSSMDSKGRSCRSGILYDNVLDWEHDLPENDLEMGVM 203
            |..|||.|........|....:.|  .|            :|::..:::.:...||...| :.|.
  Rat   191 CTVCRRSFPGEDIRADVMADRVPRCPVC------------TGVVKPDIVFFGEQLPARFL-LHVA 242

  Fly   204 HSTVADLNIALGTTLQIVPSGDLP----------LKNLKCGGKFVICNLQPTKHDKKANLIISSY 258
            ...:|||.:.|||:|::.|...|.          |.|....|.|.   |.|.:.|      :...
  Rat   243 DFALADLLLILGTSLEVEPFASLSESVQKSVPRLLINRDLVGSFA---LSPRRKD------VVQL 298

  Fly   259 VDVV--LSKVCKLLG 271
            .|||  :.::..|||
  Rat   299 GDVVQGVERLVDLLG 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt6	NP_649990.2	SIRT7	45..258	CDD:238701	66/246 (27%)
Sirt3	XP_006230588.1	SIRT1	74..308	CDD:238699	69/255 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54280
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820