Protein Alignment Sirt6 and sir-2.2

DIOPT Version :9

• Sequence 1: NP_649990.2
• Gene: Sirt6 / 41254
• FlyBaseID: FBgn0037802
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_001367227.1
• Gene: sir-2.2 / 181455
• WormBaseID: WBGene00004801
• Length: 294
• Species: Caenorhabditis elegans
• Alignment Length: 286
• Identity: 73/286 - (25%)
• Similarity: 122/286 - (42%)
• Gaps: 56/286 - (19%)

  Fly    31 AEKCQ-ELAELIKKSGHV---VLHTGAGISTSA--GIPDFRGPKGVWTLEEKGEKP----DFNVS 85
            ||.|: .|.:.|...|.|   ::.:||||||.:  ||||:|. |.|........||    |:..|
 Worm    15 AELCENSLKKFISLIGTVDKLLVISGAGISTESVPGIPDYRS-KDVGLYARIAHKPIYFQDYMRS 78

  Fly    86 -----------------FDEARPTKTHMAIIALIESGYVQYVISQNIDGLHLKSGLDRKYLSELH 133
                             |.:|.|...|.|:.....|...|::|:||:||||||:|  .|.::|||
 Worm    79 NRCRQRYWSRNFLAWPRFGQAAPNINHYALSKWEASDRFQWLITQNVDGLHLKAG--SKMVTELH 141

  Fly   134 GNIYIEQCKKC--------------------RRQFVSPSAVETVGQKSLQRACKSSMD-SKGRSC 177
            |:....:|..|                    :.:.|:|..:...|...|....:.... .:..||
 Worm   142 GSALQVKCTTCDYIESRQTYQDRLDYANPGFKEEHVAPGELAPDGDIILPLGTEKGFQIPECPSC 206

  Fly   178 RSGILYDNVLDWEHDLPENDLEMGVMHSTVADLNIALGTTLQIVPSG--DLPLKNLKCGGKFVIC 240
             .|::..:|..:..::..:.:..........|..::|||:|.:: ||  .:...|:|....|::
 Worm   207 -GGLMKTDVTFFGENVNMDKVNFCYEKVNECDGILSLGTSLAVL-SGFRFIHHANMKKKPIFIV- 268

  Fly   241 NLQPTKHDKKANLIISSYVDVVLSKV 266
            |:.||:.|..|.:.:...:..||.::
 Worm   269 NIGPTRADHMATMKLDYKISDVLKEM 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt6	NP_649990.2	SIRT7	45..258	CDD:238701	66/261 (25%)
sir-2.2	NP_001367227.1	SIRT4	27..291	CDD:238700	66/269 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910