Protein Alignment Sirt6 and LOC1273019

DIOPT Version :10

• Sequence 1: NP_649990.2
• Gene: Sirt6 / 41254
• FlyBaseID: FBgn0037802
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: XP_311957.5
• Gene: LOC1273019 / 1273019
• VectorBaseID: AGAMI1_003031
• Length: 615
• Species: Anopheles gambiae
• Alignment Length: 250
• Identity: 66/250 - (26%)
• Similarity: 102/250 - (40%)
• Gaps: 52/250 - (20%)

  Fly     7 DGLSAYDNKGILGAP-----ESFDSDEVVAEKCQELAELIKKSG---HVVLHTGAGISTSAGIPD 63
            ||....:..|  ||.     |:.|.|.|:..         .|||   .:|...||||||||||||
Mosquito   139 DGFENENGSG--GAARRRVLETVDIDGVLKH---------WKSGGFKKIVTMVGAGISTSAGIPD 192

  Fly    64 FRG----------------PKGVWTLE--EKGEKPDFNVSFD----EARPTKTHMAIIALIESGY 106
            ||.                |:.::.||  .:..||.|.::.:    ..:||.:|..:..|.:.|.
Mosquito   193 FRSPNTGLYNNLMKYNLPYPQAIFELEYLHQNPKPFFTLAKELYPGTFKPTPSHYFVRLLEQKGL 257

  Fly   107 VQYVISQNIDGLHLKSGLDRKYLSELHGNIYIEQCKKCRRQFVSPSAVETVGQKSLQRACKSSMD 171
            :....:||||.|...:|:....:.|.||..|...|.:|:..:    ::|.|.:|..       .|
Mosquito   258 LVRHYTQNIDTLERIAGIPEDKIVEAHGTFYTNHCLECKIAY----SLEFVKEKIF-------AD 311

  Fly   172 SKGRSCRSGILYDNVLDWEHDLPENDLEMGVMHSTVADLNIALGTTLQIVPSGDL 226
            ........|::..:::.:...|||....:........||.|.:||:|.:.|...|
Mosquito   312 EVPTCPCGGVIKPDIVFFGEGLPERFHMLPHQDFAECDLLIIMGTSLTVQPFASL 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt6	NP_649990.2	SIRT7	45..258	CDD:238701	54/206 (26%)
LOC1273019	XP_311957.5	SIRT1	174..422	CDD:238699	53/203 (26%)