DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3999 and GLDP1

DIOPT Version :9

Sequence 1:	NP_001262456.1	Gene:	CG3999 / 41253	FlyBaseID:	FBgn0037801	Length:	985	Species:	Drosophila melanogaster
Sequence 2:	NP_195027.1	Gene:	GLDP1 / 829438	AraportID:	AT4G33010	Length:	1037	Species:	Arabidopsis thaliana

Alignment Length:	981	Identity:	536/981 - (54%)
Similarity:	695/981 - (70%)	Gaps:	29/981 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 HRYLATTPVEEVIFPTKSD-FPSRHIGPRKTDVVAMLDTLGFKSLAELTEKAVPQSIQL--KREL 79
            |:...:..|:.|   ..|| ||.||......:...|....||..:..|.:..||:||:|  .:..
plant    62 HQQTRSISVDAV---KPSDTFPRRHNSATPDEQTHMAKFCGFDHIDSLIDATVPKSIRLDSMKFS 123

  Fly    80 DLDKPLNEHELIRRIRDISLKNQLWRSYIGMGYHNCHVPHTIIRNMFENPGWTTQYTPYQPEIAQ 144
            ..|..|.|.::|:.:.|::.||::::|:|||||:|.|||..|:||:.|||.|.|||||||.||:|
plant   124 KFDAGLTESQMIQHMVDLASKNKVFKSFIGMGYYNTHVPTVILRNIMENPAWYTQYTPYQAEISQ 188

  Fly   145 GRLESLLNYQTLVTDLTGLDVANASLLDEGTAAAEAMCLATR--HNKRKKLYLSNRVHPQTLSVV 207
            ||||||||:||::||||||.::|||||||||||||||.:...  ..|:|...:::..||||:.|.
plant   189 GRLESLLNFQTVITDLTGLPMSNASLLDEGTAAAEAMAMCNNILKGKKKTFVIASNCHPQTIDVC 253

  Fly   208 KTRTEALELEIVVGPIEQADLPSRELAGILLQYPDTYGDVKDFEDIAALAKKNGTLVVVATDLLS 272
            |||.:..:|::|...::..|..|.::.|:|:|||.|.|:|.|:.:....|..||..||:|||||:
plant   254 KTRADGFDLKVVTSDLKDIDYSSGDVCGVLVQYPGTEGEVLDYAEFVKNAHANGVKVVMATDLLA 318

  Fly   273 LTLLRPPAEFGADIAVGTSQRLGVPLGYGGPHAGFFACKQSLVRLMPGRMIGVTRDMDGNDAYRL 337
            ||:|:||.||||||.||::||.|||:|||||||.|.|..|...|:||||:||::.|..|..|.|:
plant   319 LTVLKPPGEFGADIVVGSAQRFGVPMGYGGPHAAFLATSQEYKRMMPGRIIGISVDSSGKQALRM 383

  Fly   338 ALQTREQHIRRDKATSNICTAQALLANMSAMYAIYHGPEGLKAMANRIHHFTLTLQTGV--LGAG 400
            |:||||||||||||||||||||||||||:||||:||||.|||::|.|:|........|:  ||..
plant   384 AMQTREQHIRRDKATSNICTAQALLANMAAMYAVYHGPAGLKSIAQRVHGLAGIFSLGLNKLGVA 448

  Fly   401 HEVINKNFFDTLHIRLGGGQSLEDLKERAEHKRINLRYLEDDTVGVALDETVSVADVDDLLWVFK 465
             ||....||||:.|:.....::.|...::|   ||||.::..|:..:.|||.::.|||.|   ||
plant   449 -EVQELPFFDTVKIKCSDAHAIADAASKSE---INLRVVDSTTITASFDETTTLDDVDKL---FK 506

  Fly   466 AEASVEHILARKDVLKNSIEN---SKFLRTSPYLQHPIFQSYHSESRMVRYMKKLENKDISLVHS 527
            ..||.:.:....:.|...::|   |...|.||||.||||..||:|..::||:.||::||:||.||
plant   507 VFASGKPVPFTAESLAPEVQNSIPSSLTRESPYLTHPIFNMYHTEHELLRYIHKLQSKDLSLCHS 571

  Fly   528 MIPLGSCTMKLNSTTEMMPCSFRHFTDIHPFAPVEQAQGFHQMFKELEHDLCEITGYDRISFQPN 592
            ||||||||||||:||||||.::..|||||||||||||||:.:||:.|...||.|||:|..|.|||
plant   572 MIPLGSCTMKLNATTEMMPVTWPSFTDIHPFAPVEQAQGYQEMFENLGDLLCTITGFDSFSLQPN 636

  Fly   593 SGAQGEYAGLRAIRSYHEHRNEGHRNICLIPISAHGTNPASAQMAGMKVEPIRILSNGSIDMAHL 657
            :||.||||||..||:||..|.:.|||:|:||:||||||||||.|.|||:..:...:.|:|::..:
plant   637 AGAAGEYAGLMVIRAYHMSRGDHHRNVCIIPVSAHGTNPASAAMCGMKIITVGTDAKGNINIEEV 701

  Fly   658 RAKAEEHAHELSCLMITYPSTMGVFEETVADICTLIHKHGGQVYLDGANMNAQVGLCRPGDYGSD 722
            |..||.:...|:.||:|||||.||:||.:.:||.:||::|||||:|||||||||||..||..|:|
plant   702 RKAAEANKDNLAALMVTYPSTHGVYEEGIDEICNIIHENGGQVYMDGANMNAQVGLTSPGFIGAD 766

  Fly   723 VSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPYLPGHPVVS----PLSSEEHSFGVVSAAPFGSS 783
            |.|||||||||||||||||||||||||.||||:||.|||:.    |...:....|.:||||:||:
plant   767 VCHLNLHKTFCIPHGGGGPGMGPIGVKNHLAPFLPSHPVIPTGGIPQPEKTAPLGAISAAPWGSA 831

  Fly   784 AILPISWSYIKLMGSRGLKRATQVAILNANYMSKRLEQHYKTLYKAPNSQLVAHEFILDIRDLKK 848
            .|||||::||.:|||.||..|:::||||||||:||||:||..|::..|. .||||||:|:|..|.
plant   832 LILPISYTYIAMMGSGGLTDASKIAILNANYMAKRLEKHYPVLFRGVNG-TVAHEFIIDLRGFKN 895

  Fly   849 SANIEAVDVAKRLMDYGFHAPTMSWPVAGTLMIEPTESEDKEELDRFCDAMISIREEIAEIEAGR 913
            :|.||..||||||||||||.|||||||.|||||||||||.|.||||||||:||||||||:||.|.
plant   896 TAGIEPEDVAKRLMDYGFHGPTMSWPVPGTLMIEPTESESKAELDRFCDALISIREEIAQIEKGN 960

  Fly   914 MDKAVNPLKMSPHTQAQVISDKWDRPYTREQAAFPAIFVKPDAKIWPTVGRIDDAYGDKHLVCTC 978
            .|...|.||.:||..:.:::|.|.:||:||.|||||.::: .:|.|||.||:|:.|||:.||||
plant   961 ADVQNNVLKGAPHPPSLLMADTWKKPYSREYAAFPAPWLR-SSKFWPTTGRVDNVYGDRKLVCT- 1023

  Fly   979 PPILPD 984
              :||:
plant  1024 --LLPE 1027

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3999	NP_001262456.1	PRK05367	35..981	CDD:235432	531/959 (55%)
		GDC-P	40..464	CDD:280502	213/429 (50%)
		GcvP2	494..949	CDD:223935	289/458 (63%)
GLDP1	NP_195027.1	PLN02414	1..1037	CDD:178035	536/981 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	427	1.000	Domainoid score	I111
eggNOG	1	0.900	-	-		E1_COG1003
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H141
Inparanoid	1	1.050	1060	1.000	Inparanoid score	I35
OMA	1	1.010	-	-		QHG62689
OrthoDB	1	1.010	-	-		D390348at2759
OrthoFinder	1	1.000	-	-		FOG0002904
OrthoInspector	1	1.000	-	-		otm2486
orthoMCL	1	0.900	-	-		OOG6_101195
Panther	1	1.100	-	-	LDO	PTHR11773
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2723
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840