Protein Alignment CG42795 and Usp6nl

DIOPT Version :10

• Sequence 1: NP_001287272.1
• Gene: CG42795 / 41252
• FlyBaseID: FBgn0261928
• Length: 3213
• Species: Drosophila melanogaster
• Sequence 2: NP_852064.2
• Gene: Usp6nl / 98910
• MGIID: 2138893
• Length: 842
• Species: Mus musculus
• Alignment Length: 1001
• Identity: 192/1001 - (19%)
• Similarity: 312/1001 - (31%)
• Gaps: 345/1001 - (34%)

  Fly   191 PSATAAADD------EATSDYNQWLHAM----------KLVARLPGGTPPEFRRKLWLSL----- 234
            |...||||.      |.||   :||..:          |...|:..|.|.:.|.::|..|
Mouse    80 PYHNAAADRQKQLEIERTS---KWLKMLKKWERYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPK 141

  Fly   235 -----ADKYLKSKNVDWAQQREKCFCEEWREDDEELGIQIVKDLHRT-GSNLCTGPAGSINQAKL 293
                 .|.|.|.|:      |.:....:.|        ||..|::|| ..::.......:.|..|
Mouse   142 MKEETRDLYSKLKH------RARGCSPDIR--------QIDLDVNRTFRDHIMFRDRYGVKQQSL 192

  Fly   294 KRILLGYARYNPEVGYCQGFNMLGALILQVMDKEEEESMKVMIYLVEGVLPT----GYFYGSMGG 354
            ..:|..|:.||.|||||||.:.:.||:|..|:  ||::...::.|..|  |.    |:|......
Mouse   193 FHVLAAYSIYNTEVGYCQGMSQITALLLMYMN--EEDAFWALVKLFSG--PKHAMHGFFVQGFPK 253

  Fly   355 LQADMGVFRELMQTRLPRLAKHLQRLQGPVENAFEPPLTNVFTMQWFLTMFCTCLPMSCVLRVWD 419
            |........:::...|.:|.:||..         :...|:.:||:||...|....|....||:||
Mouse   254 LLRFQEHHEKILNKFLSKLKQHLDS---------QEIYTSFYTMKWFFQCFLDRTPFRLNLRIWD 309

  Fly   420 LVLIEGSDVLLRTALVLWSLLEERVISVRSADEFYGKMGSYSSELLNGHLVDSNGLIERVVKLGP 484
            :.:.||..||  ||:                        ||:
Mouse   310 IYIFEGERVL--TAM------------------------SYT----------------------- 325

  Fly   485 IEDLRQLRDKHLYNIAPLRHKQGLQL-----YYDEEDTHSDEERLAVATVFGLNWGRRGSVGPAA 544
               :.:|..|||..::.....:.||.     ::.|:|...::.::::|.:      :|..:....
Mouse   326 ---ILKLHKKHLMKLSMEELVEFLQETLAKDFFFEDDFVIEQLQVSMAEL------KRAKLDLPE 381

  Fly   545 AGKQQVEQKDRLALDISLLKKQYDRLRERQKQAHVILTTACSTAARQGSGPASSSQPAVPVNQLL 609
            .||:.           ...||...:|...         :||......|              |..
Mouse   382 PGKED-----------EYPKKPLGQLPPE---------SACVNHLSNG--------------QRS 412

  Fly   610 LGRPAIVTNKGKRVGAPLGAIPPARKPSLPAVLHTKPTSEKQLRRGETLLWRDTDPSRRRRDSLT 674
            :|||:..|:..:..|:|       ||....:.:|..               |:..|.|..:..
Mouse   413 VGRPSPKTSSRREDGSP-------RKNHEHSPVHHS---------------RNGTPERAGQSR-- 453

  Fly   675 WKEIKADRAAMIREGVDVSSVRTQKLRTRFGKSDSSSYSEDSDGEQESG-----TGGGGGSSTDT 734
                        |:.||..|...        |.::.|..:.|.|.|:|.     ......|:..:
Mouse   454 ------------RKSVDEGSKNL--------KHEAESQRKPSPGMQDSSRHYNHAAANQNSNAIS 498

  Fly   735 SLCDDDDPKSTEKSPKQKAKLARKLK---EQKQ----------LAGSRETSLERQRPKSWAPSSH 786
            ::..:..||  .:.|...:.:.|..|   |.|.          :.||.||.|...|.|
Mouse   499 NVRKEFMPK--WRKPSDASAIERTTKYAVEGKSHSALPALPVAIPGSAETRLPNSRQK------- 554

  Fly   787 EIPFMLMGTDSGDEKEDKSTKE-GPITGDQAEDSATESGHYEFDRELHLVSSKMEPLKLPFDPEF 850
                 :...|.|:.|...:..: ..:.|.::|..|:..   |.....|..|.:..|
Mouse   555 -----MKALDGGEGKRGSNASQYDNVPGGESEHGASAE---EGPERTHPHSPRKHP--------- 602

  Fly   851 TGMTSVSPIPTPREKSEAEEDLLDERKPFDVSDDGVTNQYFERVNSVERPNRLELTYSLNEEETD 915
                  .|.|:|.:                     |.|::   ...|:.|:.:.....|.||  |
Mouse   603 ------EPSPSPPK---------------------VPNKF---TFKVQPPSHVRYPPQLPEE--D 635

  Fly   916 TNAIYLEEREKVEGHSGDREYNSLPPFY----PRENDDGVQGGGKV-----PQIRDDNIPGENKD 971
            ..|.|            ...|:: ||.|    |:.......|....     |||.....|
Mouse   636 HRAAY------------PPSYSN-PPVYHGNSPKHVPTAHSGFVSTQISPRPQINPSRRP----- 682

  Fly   972 DYKELLSMTIEENTVYKPPTPTASTLSNASRKRRDPRRKTLTRSSTIEIEERYQALERRISQDQP 1036
             |...||:.......|..|||                  .:..||.||:...........|...|
Mouse   683 -YGSSLSVDTSPEKAYSRPTP------------------VVLPSSRIEVLPIDMGARGYGSSGSP 728

  Fly  1037 SGDR----QAKYIPSTAALEERFNTLEKQL-----SAEKQRKELSEME-----AEYPIKSERIPS 1087
            ...:    ...|:|......|...|...::     :.:..|..||.:.     ...|.::..:|.
Mouse   729 KNGQFILPPVDYLPENRKWSEVSYTYRPEMHGQSWTRDAHRSHLSNLPNYAAFQHIPFQAHGLPE 793

  Fly  1088 -TADLESRFNSLTKQMSSSESSSKTP 1112
             :.|...|:     :||::...:..|
Mouse   794 VSVDSPVRY-----KMSAAVEDASPP 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42795	NP_001287272.1	RabGAP-TBC	268..443	CDD:459855	51/179 (28%)
		DUF4682	560..689	CDD:464830	20/128 (16%)
		PTZ00121	<1112..2009	CDD:173412	1/1 (100%)
		PTZ00121	<1740..2340	CDD:173412
		PTZ00449	<2270..2610	CDD:185628
Usp6nl	NP_852064.2	TBC	120..335	CDD:214540	67/293 (23%)
		PTZ00449	<526..>738	CDD:185628	55/304 (18%)