Protein Alignment CG42795 and MSB3

DIOPT Version :10

• Sequence 1: NP_001287272.1
• Gene: CG42795 / 41252
• FlyBaseID: FBgn0261928
• Length: 3213
• Species: Drosophila melanogaster
• Sequence 2: NP_014106.1
• Gene: MSB3 / 855423
• SGDID: S000005237
• Length: 633
• Species: Saccharomyces cerevisiae
• Alignment Length: 338
• Identity: 81/338 - (23%)
• Similarity: 148/338 - (43%)
• Gaps: 65/338 - (19%)

  Fly   199 DEATSDYNQWLHAMKLVARLPGGTPPEFRRKLWLSLA---DKYLKSKNVDWAQQREKCFCEEWRE 260
            |::.|.:......:|...|  .|.|.|:|...|...|   :|..|:|.| ::|...| ..:..::
Yeast   203 DDSPSRFPSKSERLKRYVR--KGIPAEWRGNAWWHFARGQEKLNKNKGV-YSQLLRK-MKQIKKQ 263

  Fly   261 DDEELGIQ----IVKDLHRT-------GSNLCTGPAGSINQAKLKRILLGYARYNPEVGYCQGFN 314
            :..|..:|    |.:||:||       .|:|.......|.:: |:|:|:.::.|||::||||..|
Yeast   264 NPNEKQVQDLDIIERDLNRTFPDNIHFQSSLHNKEGPPIIKS-LRRVLVAFSLYNPKIGYCQSMN 327

  Fly   315 MLGALILQVMDKEEEESMKVMIYLVEGVLPTGYFYGSMGGLQADMGVFRELMQTRLPRL------ 373
            .|..|:|..:|  ||.:..:::.:....|| |....::.|:..|.||....::..:|.:
Yeast   328 FLAGLLLLFLD--EERAFWMLVIITSRYLP-GVHNINLEGVNIDQGVLMLCVKEYIPEVWSYIKP 389

  Fly   374 -AKHLQR------------LQGPVENAF---EPPLTNVFTMQWFLTMFCTCLPMSCVLRVWDLVL 422
             ..|.|:            |....:|.|   .||:| :.|..||::.|...:|:...||:||.:.
Yeast   390 SIDHHQKNNKTFSPSNKKVLFNMQKNEFLYRLPPIT-LCTASWFMSCFVGVVPIETTLRIWDCLF 453

  Fly   423 IEGSDVLLRTALVLWSLLEERVISVR------------SADEFYGKMGSYSSEL--------LNG 467
            .|.|..|.:.:|.:..|.|..:..::            :.::..|.||...|::        ...
Yeast   454 YEESHFLFKVSLAVLKLSEHDLSKIKPRNNSLNYSWGSNLNQRGGSMGQEDSDMEIFQVIQTFPK 518

  Fly   468 HLVDSNGLIERVV 480
            .|::.|.:.|:::
Yeast   519 TLLNPNEIFEKII 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42795	NP_001287272.1	RabGAP-TBC	268..443	CDD:459855	57/207 (28%)
		DUF4682	560..689	CDD:464830
		PTZ00121	<1112..2009	CDD:173412
		PTZ00121	<1740..2340	CDD:173412
		PTZ00449	<2270..2610	CDD:185628
MSB3	NP_014106.1	COG5210	15..540	CDD:227535	81/338 (24%)