Protein Alignment CG42795 and Tbc1d21

DIOPT Version :10

• Sequence 1: NP_001287272.1
• Gene: CG42795 / 41252
• FlyBaseID: FBgn0261928
• Length: 3213
• Species: Drosophila melanogaster
• Sequence 2: NP_083130.1
• Gene: Tbc1d21 / 74286
• MGIID: 1921536
• Length: 336
• Species: Mus musculus
• Alignment Length: 306
• Identity: 64/306 - (20%)
• Similarity: 122/306 - (39%)
• Gaps: 75/306 - (24%)

  Fly   218 LPGGTPPEFRRKLWLSLADKYLKSKNVDWAQQREK-------------CFCEEWREDDEELGIQ- 268
            |..|..|..|.:.|..|...|      .|...|::             ..|:.:.:      ||
Mouse    54 LERGLHPFVRTEAWKFLTGYY------SWQSSRDERLMVDSNRRRNYNSLCQMYEK------IQP 106

  Fly   269 IVKDLH----RTGSNLC--------TGPAGS--INQAKL-KRILLGYARYNPEVGYCQGFNMLGA 318
            ::::||    .|.:|:.        ..|.|:  |::.|| |.:||.|. .|.:..|.:||:.: .
Mouse   107 LLENLHGNFTETRNNIAYDIQRLYDKDPLGNVLIDKKKLEKTLLLSYV-CNTKAEYQRGFHEM-V 169

  Fly   319 LILQVMDKEEEESMKVMIYLVEGVLPTGYFYGSMGGLQADMGVFRELMQTRLPRLAKHLQ-RLQG 382
            ::.|:|.:.:.|:..:..:.::   .|.:......|:..::.:...|:....|..|:||: :..|
Mouse   170 MLFQLMVEHDHETFWLFQFFLQ---KTEHSCVINIGVGKNLDMLNSLITLLDPEFAEHLKGKGSG 231

  Fly   383 PVENAFEPPLTNVFTMQWFLTMFCTCLPMSC-----VLRVWDLVLIEGSDVLLRTALVLWSLL-- 440
            .|::.|          .|    ||.|...:.     |.|:|: ||:.|........||.:|:|
Mouse   232 AVQSLF----------PW----FCLCFQRAFKTFDDVWRLWE-VLLTGKPCRNFQVLVAYSMLQM 281

  Fly   441 --EERVISVRSADEFYGKMGSY----SSELLNGHLVDSNGLIERVV 480
              |:.::...|.|.......:.    :.||::...|..:.|:::.|
Mouse   282 VREQALLECMSGDAILMACNNLIDLDADELISAACVVYSELMQKEV 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42795	NP_001287272.1	RabGAP-TBC	268..443	CDD:459855	46/200 (23%)
		DUF4682	560..689	CDD:464830
		PTZ00121	<1112..2009	CDD:173412
		PTZ00121	<1740..2340	CDD:173412
		PTZ00449	<2270..2610	CDD:185628
Tbc1d21	NP_083130.1	TBC	62..287	CDD:214540	54/256 (21%)