DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42795 and Tbc1d15

DIOPT Version :10

Sequence 1:NP_001287272.1 Gene:CG42795 / 41252 FlyBaseID:FBgn0261928 Length:3213 Species:Drosophila melanogaster
Sequence 2:NP_001414153.1 Gene:Tbc1d15 / 66687 MGIID:1913937 Length:688 Species:Mus musculus


Alignment Length:351 Identity:74/351 - (21%)
Similarity:125/351 - (35%) Gaps:97/351 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   210 HAMK------LVARLPGGTPPEFRRKLWLSLADKY----LKSKNVDWAQQREKCFCEEWREDDEE 264
            |:::      |:...|..:..|.|.:|.....|:|    |:.|:|..||::......::|.    
Mouse   349 HSLRKQAWKFLLGYFPWDSTKEERTQLQKQKTDEYFRMKLQWKSVSEAQEKRNSRLRDYRS---- 409

  Fly   265 LGIQIVKDLHRTG-SNLCTGPAGSINQAKLKRILLGYARYNPEVGYCQGFNMLGALILQVMDKEE 328
               .|.||::||. :|.......:.....|..||:.|..|:.::||.||.:.|.:.:|.||:.|.
Mouse   410 ---LIEKDVNRTDRTNKFYEGQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEV 471

  Fly   329 EESMKVMIYLVEGVLPTGYFYGSMGGLQADMGVFRELMQ---TRLPRLAKHLQRLQGPVENAFEP 390
            :...              .|...|..:..:   |.|.||   |:|.:|:..|:.|.....:..|.
Mouse   472 DAFW--------------CFASYMDQMHQN---FEEQMQGMKTQLIQLSTLLRLLDSGFCSYLES 519

  Fly   391 PLTN--VFTMQWFLTMFCTCLPMSCVLRVWDLVLIEGSDVLLRTALVLWSLLEERVISVRSADEF 453
            ..:.  .|..:|.|..|........:||:|:               |:|:.|..:          
Mouse   520 QDSGYLYFCFRWLLIRFKREFSFLDILRLWE---------------VMWTELPCK---------- 559

  Fly   454 YGKMGSYSSELLNGHLVDSNGLIERVVKLGPIEDLRQLRDKHLYNIAPLRHKQGLQLYYDEEDTH 518
                        |.||:....::|        .:.:|:..||......|:|...|.:..|.||..
Mouse   560 ------------NFHLLLCCAILE--------SEKQQIMAKHYGFNEILKHINELSMKIDVEDIL 604

  Fly   519 SDEERL------------AVATVFGL 532
            ...|.:            ||..:.||
Mouse   605 CKAEAISLQMAQCKELPQAVCEILGL 630

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42795NP_001287272.1 RabGAP-TBC 268..443 CDD:459855 42/180 (23%)
DUF4682 560..689 CDD:464830
PTZ00121 <1112..2009 CDD:173412
PTZ00121 <1740..2340 CDD:173412
PTZ00449 <2270..2610 CDD:185628
Tbc1d15NP_001414153.1 PH_RBD 10..211 CDD:432305
TBC 343..578 CDD:214540 61/297 (21%)
Blue background indicates that the domain is not in the aligned region.

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