Protein Alignment CG42795 and Sgsm1

DIOPT Version :10

• Sequence 1: NP_001287272.1
• Gene: CG42795 / 41252
• FlyBaseID: FBgn0261928
• Length: 3213
• Species: Drosophila melanogaster
• Sequence 2: XP_006535185.1
• Gene: Sgsm1 / 52850
• MGIID: 107320
• Length: 1148
• Species: Mus musculus
• Alignment Length: 1054
• Identity: 192/1054 - (18%)
• Similarity: 317/1054 - (30%)
• Gaps: 363/1054 - (34%)

  Fly   469 LVDS-----NGLIERVVKLGPIEDLRQLRDKHLYNIAPLRHK----------QGLQLYYDEEDTH 518
            |::|     .||.|.|.||..:.:|..|..|||:....|..:          :....||::|...
Mouse    97 LIESARNQIQGLQENVRKLPKLPNLSPLAIKHLWIRTALFERVLDKIVHYLVENSSKYYEKEALL 161

  Fly   519 SDE-ERLAVATVFGLNWGRRGSVGPAAAGKQQVEQKDRLALDISLLKKQYDRL--RERQKQAHVI 580
            .|. :...:|::.         |||.|....:::..|....|.|.     |.|  |.|...:|:.
Mouse   162 MDPVDGPILASLL---------VGPCALEYTKMKTADHFWTDPSA-----DELVQRHRIHSSHLR 212

  Fly   581 LTTACSTAA-----RQGSGPASSSQPAVPVNQ------------LLLGRPAIVTNKGKRVGAPLG 628
            ..:.....|     |..|| :...:|::....            ||.|:..::..
Mouse   213 QDSPTKRPALCIQKRHSSG-SMDDRPSISARDYVESLHQNSRATLLYGKNNVLVQ---------- 266

  Fly   629 AIPPARKPSLPAVLHTKPTSEKQLRRGETLLWRDTDPSRRRRDSLTW-KEIKADRAAMIR----- 687
              |.....::|..|....|::..     ||.|............|.: |.:..|.|..||
Mouse   267 --PRDDMEAVPGYLSLHQTADVM-----TLKWTPNQLMNGSVGDLDYEKSVYWDYAVTIRLEEIV 324

  Fly   688 -----EGVD-------VSSVRTQKLRTRFGKSDSSSYSEDSDGEQESGTGGGGGSSTDTSLCDDD 740
                 :.||       ||....|:...||.|                     ||.......|.::
Mouse   325 YLHCHQQVDSGGTVVLVSQDGIQRPPFRFPK---------------------GGHLLQFLSCLEN 368

  Fly   741 --------DPKSTEKSPKQKAKLARKLKEQKQLAGSRETSLERQRPKSWAPSSHEIPFMLMGTDS 797
                    ||...  |.:.|.|:..||:::.....|..||
Mouse   369 GLLPHGQLDPPLW--SQRGKGKVFPKLRKRSPQGSSESTS------------------------- 406

  Fly   798 GDEKEDKSTKEGPITGDQAED-------SATESGHYEFDRELHLVSSKMEPLKLPFDPEFTGMTS 855
             .:|||          |:|.|       ..|:|.....|    |:.|   |..:...|.:..:.
Mouse   407 -SDKED----------DEATDYVFRIIYPGTQSEFVALD----LMGS---PRPVSIGPAWMMLA- 452

  Fly   856 VSPIPTPREKSEAEEDLLDERKPFDVSDDGVTNQYFERVNSVERPNRLELTYSLNEEETDTNAIY 920
                        |.:.:|...|..         |:.:....:..|.|                 .
Mouse   453 ------------AGQSMLVVAKGL---------QWAQTRGCLTIPTR-----------------S 479

  Fly   921 LEEREKVEGHSGDREYNSLPPFY---PRE------NDDGVQGGGKVPQIRDDNIPGENKDDYKEL 976
            ::|:..:.....|...|:|||.:   ||:      :..|...||.......:..|       .:|
Mouse   480 VKEQPPMPQDLMDVSMNNLPPLWQPSPRKSSCSSCSQSGSADGGSTNGCNHERAP-------LKL 537

  Fly   977 LSMTIEENTVYKPPTPTASTLSNASRKRRDPRRKTLTRS-----------STIEIEERYQALERR 1030
            |.    :|..|                      :.|:|:           ||:............
Mouse   538 LC----DNMKY----------------------QILSRAFYGWLAYCRHLSTVRTHLSALVNHMI 576

  Fly  1031 ISQDQPSGDRQA-------KYIPSTAALEER-------FNTLEKQL---------------SAEK 1066
            :|.|.|....|.       |||..:....|:       :..::.::               ..|.
Mouse   577 VSPDLPCDAGQGLTASIWEKYIQDSTTYPEQELLRLIYYGGVQPEIRRAVWPFLLGHYQFGMTEM 641

  Fly  1067 QRKELSE-MEAEYP------IKSERIPSTADLESRFNSLTKQMSSSESSSKTPIDLKDEDRPSGS 1124
            :|||:.| :.|.|.      :..|.|....:.||...:|.|..|.:...|.....|..:...|..
Mouse   642 ERKEVDEQIHACYAQTMSEWLGCEAIVRQRERESHAAALAKCSSGASLDSHLHRMLHRDSTISNE 706

  Fly  1125 SSKNQKDSEKTSKLHKSEEPESNTKETTGETEASDSNDSKIGEKETEQPRIKKLPSTAELEDRFN 1189
            ||::.....:..:|.......:...|:..|.|.:::.    |..|.:.|   |:|:.
Mouse   707 SSQSCSSGRQNLRLQSDSSSSTQVFESVDEVEQTEAE----GRSEEKHP---KIPNG-------- 756

  Fly  1190 ALERKMSVQKSSPSKNKKEPPDEEESKSTKEPEEPEESEKANEKTSGRQTPIAKK--DSKDSDQK 1252
                  :....:.|.:...|.....|....|..||..|.:.:...:.|..|...:  ||...|.:
Mouse   757 ------NPANGTCSPDSGHPSSHNFSSGLSEHSEPSLSTEDSVLDAQRSLPAVFRPGDSSVEDGQ 815

  Fly  1253 KSETKENQSPTKNQDEKVKVKSPKSEEMIEKETSSNPKEDSHESEAATNKKVEGNRELSSEKG-- 1315
            .||.      |.::||     :|:.|..:         :||.||:...|:.:|   |..|..|
Mouse   816 SSEA------TTSRDE-----APREELAV---------QDSLESDLLANESLE---EFMSIPGSL 857

  Fly  1316 DHKIKEKS----EEAPGKAGKETAETKNANVKDSSKKGDSQKNEAAKTSVSQTESDLKPSSKENS 1376
            |..:.||.    :..||:|             |...:.||:.|.:.:..:    ..|.|:....:
Mouse   858 DVALPEKDGAVMDGWPGEA-------------DKPSRADSEDNLSEEPEM----ESLFPALASLA 905

  Fly  1377 TSKDAEQEKTPRKS 1390
            .:..|..|.:|..|
Mouse   906 VTSSANNEASPVSS 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42795	NP_001287272.1	RabGAP-TBC	268..443	CDD:459855
		DUF4682	560..689	CDD:464830	27/158 (17%)
		PTZ00121	<1112..2009	CDD:173412	57/287 (20%)
		PTZ00121	<1740..2340	CDD:173412
		PTZ00449	<2270..2610	CDD:185628
Sgsm1	XP_006535185.1	RUN_SGSM1	20..196	CDD:439065	25/107 (23%)
		PH_RUTBC	254..425	CDD:275431	43/246 (17%)
		TBC	<936..1105	CDD:214540