Protein Alignment CG42795 and RN-tre

DIOPT Version :10

• Sequence 1: NP_001287272.1
• Gene: CG42795 / 41252
• FlyBaseID: FBgn0261928
• Length: 3213
• Species: Drosophila melanogaster
• Sequence 2: NP_652381.1
• Gene: RN-tre / 36554
• FlyBaseID: FBgn0020620
• Length: 571
• Species: Drosophila melanogaster
• Alignment Length: 613
• Identity: 135/613 - (22%)
• Similarity: 218/613 - (35%)
• Gaps: 200/613 - (32%)

  Fly   206 NQWLHAM-KLVARLPGGTPPEFRRKLWLSLAD----------KYLKSKNVDWAQQREKCFCEEWR 259
            |||.... ||..|:..|.|...|...|..|.|          .||:      ..|..:.:..|.|
  Fly    87 NQWPPPQDKLHKRVYKGIPDRVRMVAWNKLLDIQQSINNNAGVYLR------MLQLARKYSTETR 145

  Fly   260 EDDEELGIQIVKDLHRTGSNLCTGPAGSINQAKLKRILLGYARYNPEVGYCQGFNMLGALILQVM 324
            :.|.::..|. :|      ||......|:.|..|..:|..|:.||.|:|||||...:..::|..:
  Fly   146 QIDADVNRQF-RD------NLAFRERYSVKQCSLFNVLNAYSIYNSELGYCQGMACVAGVLLLYL 203

  Fly   325 DKEEEESMKVMIYLVEGVLPTGYFYGSMGGLQADMGVFRELMQTRLPRLAKHLQRLQGPVENAFE 389
            .:||       .:.....|.|...||.       .|:|.|.. .:|.|...|..|:...:.....
  Fly   204 HEEE-------AFWALNTLITDQKYGM-------HGLFIEGF-PKLTRFIDHHDRIMSKIMRKLH 253

  Fly   390 PPLTN------VFTMQWFLTMFCTCLPMSCVLRVWDLVLIEGSDVLLRTALVLWSLLEERVISVR 448
            ...|.      ::.::||..:|...:|.|..|||||:.:::|..|:|..|:.:..|.::.::.::
  Fly   254 KHFTKHNVDALLYAIKWFFVVFVERVPFSLSLRVWDIFMLDGDRVILSMAITILYLHKDELLRLK 318

  Fly   449 SADEF-------YGKMGSYSSELLNGHLVDSNGLIERVVKLGPIEDL---------------RQL 491
            ..|..       ..|...||.:       |:...:|||:|  .::||               |:|
  Fly   319 DMDAIIEYLQVRLHKNFGYSDD-------DAIQALERVMK--KLKDLKLDVPPPAKSNEFPTRKL 374

  Fly   492 RDKHLYNIAPLRHKQGLQLYYDEEDTHSDEERLAVATVFGLNWGRRGSVGPAAAGKQQVEQKDRL 556
            .|   :..|.:..|.|.:     .:.::|.|:..:..|                    :.::::.
  Fly   375 GD---FVEADMEKKIGRR-----RNDYTDAEKQVITDV--------------------ISRQEQN 411

  Fly   557 ALDISLLKKQYDRLRERQKQAHVIL-TTACSTAARQGSG---------------PASSSQPAVPV 605
            |:|:               |:.|.. |:.|:|    |.|               ||:||..
  Fly   412 AIDV---------------QSTVSYETSECAT----GDGYSMKTFESITSLATSPANSSYS---- 453

  Fly   606 NQLLLGRPAIVTNKGKRVGAPLGAIPPARKPSL---------PAVLHTKPTSEKQLRRGETLLWR 661
               |.....:||......       .|||..|:         ||:   .|...:.:|...:   .
  Fly   454 ---LYSNGFVVTTIDSEQ-------DPARSQSIHNLSYLQTHPAL---PPNGLQHMRHSFS---S 502

  Fly   662 DTDPSRRRRDSLTWKEIKADRAAMIREGVDVSSVRTQKLRTRFGKSDSSS--YSEDSDGEQESGT 724
            |:| ||.|        |..|:|..:        ::.|:|... .|:.||.  |...:
  Fly   503 DSD-SRNR--------IDLDQALEV--------LQRQQLPLH-PKTPSSQVVYIVQN-------- 541

  Fly   725 GGGGG----SSTDTSLCDDDDPKSTEKS 748
            |||||    ...|.:..||||..|.|.:
  Fly   542 GGGGGRYMDGHRDAADDDDDDALSVENT 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42795	NP_001287272.1	RabGAP-TBC	268..443	CDD:459855	47/180 (26%)
		DUF4682	560..689	CDD:464830	30/153 (20%)
		PTZ00121	<1112..2009	CDD:173412
		PTZ00121	<1740..2340	CDD:173412
		PTZ00449	<2270..2610	CDD:185628
RN-tre	NP_652381.1	TBC	100..315	CDD:214540	59/242 (24%)