DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42795 and Tbc1d8b

DIOPT Version :10

Sequence 1:NP_001287272.1 Gene:CG42795 / 41252 FlyBaseID:FBgn0261928 Length:3213 Species:Drosophila melanogaster
Sequence 2:NP_001388066.1 Gene:Tbc1d8b / 315912 RGDID:1563084 Length:1118 Species:Rattus norvegicus


Alignment Length:386 Identity:95/386 - (24%)
Similarity:162/386 - (41%) Gaps:92/386 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   214 LVARLPGGTPPEFRRKLWLSLADKYLKSKNVDWAQQREKCFCEEWREDDEELGI------QIVKD 272
            ||.|   |.|...|.:||:      |.|..|:........:.|   ..::.||.      :|.:|
  Rat   482 LVVR---GIPETLRGELWM------LFSGAVNDMAANPGYYAE---VVEQSLGTSNLATEEIERD 534

  Fly   273 LHRTGSNLCTGPA--GSINQAKLKRILLGYARYNPEVGYCQGFNMLGALILQVMDKEEEESMKVM 335
            |.|   :|...||  .....:.|:|:|..||..||::||||..|:|.:::|  :..:|||:..::
  Rat   535 LRR---SLPEHPAFQSDTGISALRRVLTAYAYRNPKIGYCQAMNILTSVLL--LYAKEEEAFWLL 594

  Fly   336 IYLVEGVLPTGYFYGSMGGLQADMGVFRELMQTRLPRLAKHLQRLQGPVENAFEPPLTNVFTMQW 400
            :.:.|.:|| .||...:.|...|..||.||::..||:|..|:.          :....:..::.|
  Rat   595 VAVCERMLP-DYFNRRIIGALVDQAVFEELIRDHLPQLTDHMT----------DMTFFSSVSLSW 648

  Fly   401 FLTMFCTCLPMSCVLRVWDLVLIEGSDVLLRTALVLWSLLEERVI-------SVRSADEFYG--- 455
            |||:|.:.||:...:.|.|....:|...:|:..|.:.....::::       :|.:.:.|:.   
  Rat   649 FLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLTCKDDAEAVTALNRFFDNVI 713

  Fly   456 ----------KMGSYSSELLNGHL-VDSNGLI-ERVVKLGPI--EDLRQLRDKH-LYNIAPLRHK 505
                      :.||..::..:.|. ||...|| |...|.|.|  ||:..:|.:: ||.|..|   
  Rat   714 NKDSPLPSNVQQGSNINDGKSNHAKVDITDLIRESNEKYGSIRYEDIHSMRCRNRLYVIQTL--- 775

  Fly   506 QGLQLYYDEEDTHSDEERLAVATVFGLNWGRRGSVGPAAAGKQQVEQKDRLALDISLLKKQ 566
                    ||.|..:..|:....|                 |..:::.|.|.:   :.||:
  Rat   776 --------EETTKQNVLRVVSQDV-----------------KMSLQELDELYV---IFKKE 808

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42795NP_001287272.1 RabGAP-TBC 268..443 CDD:459855 51/176 (29%)
DUF4682 560..689 CDD:464830 2/7 (29%)
PTZ00121 <1112..2009 CDD:173412
PTZ00121 <1740..2340 CDD:173412
PTZ00449 <2270..2610 CDD:185628
Tbc1d8bNP_001388066.1 PH-GRAM1_TBC1D8B 156..254 CDD:275419
PH-GRAM2_TBC1D8B 296..388 CDD:270159
TBC 485..693 CDD:214540 63/235 (27%)
Blue background indicates that the domain is not in the aligned region.

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