DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Timp and TIMP1

DIOPT Version :9

Sequence 1:NP_731461.1 Gene:Timp / 41248 FlyBaseID:FBgn0025879 Length:210 Species:Drosophila melanogaster
Sequence 2:XP_016885255.1 Gene:TIMP1 / 7076 HGNCID:11820 Length:261 Species:Homo sapiens


Alignment Length:90 Identity:23/90 - (25%)
Similarity:32/90 - (35%) Gaps:23/90 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    87 LSTPQDDAMCGINLDLGKVYIVAGRMPTLNICSYYKEYTRMTITERHGFSGGY-AKATNCTV--- 147
            ||.|......| .|..|.::|..        ||:...:..:::.:|.||:..| .....|||   
Human    94 LSVPAPPFSLG-KLQDGLLHITT--------CSFVAPWNSLSLAQRRGFTKTYTVGCEECTVSAW 149

  Fly   148 TPCFGERCFKGRNYADTCKWSPFGK 172
            |.....|.|.|          ||.|
Human   150 TLTSNGRSFPG----------PFPK 164

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TimpNP_731461.1 TIMP 26..197 CDD:279332 23/90 (26%)
TIMP1XP_016885255.1 NTR_like <104..>147 CDD:295338 12/51 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 68 1.000 Domainoid score I9709
eggNOG 1 0.900 - - E1_KOG4745
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 73 1.000 Inparanoid score I5293
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG47496
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000998
OrthoInspector 1 1.000 - - otm41155
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11844
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4784
SonicParanoid 1 1.000 - - X655
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1211.960

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