DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Timp and timp4.2

DIOPT Version :9

Sequence 1:	NP_731461.1	Gene:	Timp / 41248	FlyBaseID:	FBgn0025879	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_001315189.1	Gene:	timp4.2 / 108004535	ZFINID:	ZDB-GENE-160114-61	Length:	187	Species:	Danio rerio

Alignment Length:	198	Identity:	55/198 - (27%)
Similarity:	87/198 - (43%)	Gaps:	33/198 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GLLTLLLVAVFAFYGRPADACSCMPSHPQTHFAQADYVVQLRVLRKSDT--IEPGRTTYKVHIKR 70
            |||..:.|.:   ..:..:||||:|.|||..|..:..|::..||.:...  .:|....||:::.:
Zfish    11 GLLFFMCVCL---NEQMLEACSCIPFHPQQEFCYSSAVIKAMVLDEEPIPGQDPEEIKYKINVLQ 72

  Fly    71 TYKATSEARRMLRDG--RLSTPQDDAMCGINLDLGKVYIVAGRMPTLNICSYYKEYTRMTITERH 133
            .:|....|      |  .|.|..|.|||||.|..| :|::|.|...:.:|.....:..::.|.:.
Zfish    73 VFKGAEHA------GIEYLHTASDGAMCGIRLRPG-IYLLAVRGVHVGLCDLVVRWDNLSKTHKK 130

  Fly   134 GFSGGYAKATNCTVTPCFGERCFKGRNYA----DTCKWSPFGKCETNYSACMPHKVQTVNGVISR 194
            ..|.| .:|.:|.|:.||.|.|.:.:.|.    |:.|.       .:.|.||.:..       ..
Zfish   131 ILSLG-QEACDCKVSHCFKEPCDENKCYLTDMFDSVKL-------YSESICMANST-------GS 180

  Fly   195 CRW 197
            |||
Zfish   181 CRW 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Timp	NP_731461.1	TIMP	26..197	CDD:279332	49/178 (28%)
timp4.2	NP_001315189.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9074
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	75	1.000	Inparanoid score	I5261
OMA	1	1.010	-	-		QHG47496
OrthoDB	1	1.010	-	-		D1122531at2759
OrthoFinder	1	1.000	-	-		FOG0000998
OrthoInspector	1	1.000	-	-		otm24223
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11844
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X655
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	10.080