| Sequence 1: | NP_731459.2 | Gene: | Syn / 41247 | FlyBaseID: | FBgn0004575 | Length: | 1041 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001356836.1 | Gene: | SYN3 / 8224 | HGNCID: | 11496 | Length: | 580 | Species: | Homo sapiens |
| Alignment Length: | 645 | Identity: | 237/645 - (36%) |
|---|---|---|---|
| Similarity: | 330/645 - (51%) | Gaps: | 127/645 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 14 VNFLKRRFSSGDLSSEVDDVDPNS-LPPAARPIQDQPTKPPVAGGPPNMPPPP--APGQPAGAAP 75
Fly 76 ELSLSFGAGKTP-ATAAPAPPRGVSAPTSPAKSRESLLQRVQSLTGAARDQGASILGAAVQSATQ 139
Fly 140 RAPAFSKDKYFTLLVLDDQNTDWSKYFRGRRLHGDFDIRVEQAEFRDITVVSSADTGPVVTMAAY 204
Fly 205 RSGTR-VARSFRPDFVLIRQPPRDGS--SDYRSTILGLKYGGVPSINSLHSIYQFQDKPWVFSHL 266
Fly 267 LQLQRRLGRDGFPLIEQTFFPNPRDLFQFTKFPSVLKAGHCHGGVATARLENQSALQDAAGLVSG 331
Fly 332 AGNDSHCYCTIEPYIDAKFSVHIQKIGNNYKAFMRKSITGNWKTNQGSAMLEQITLTEKYKSWVD 396
Fly 397 EISELFGGMEVCGLSVVVAKDGREYIISACDSTFALIGDTQEEDRRQIADLVSGRMQNVCRPSMA 461
Fly 462 QTGPGKLPSRSSVSSRAESPTDEGVAPTPPLPAGPRPAPMGGP----PPIPERT----------- 511
Fly 512 -----SPAVGS-----------IGRLSSRSSISEVPEEPSSSG--------PSTVGGVRRDSQ-- 550
Fly 551 --------------TSQSSTISSSVSRAGQRPPQTQNSVVEDAEDTMKNLRKTFAGIFGD 596 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Syn | NP_731459.2 | Synapsin | 151..246 | CDD:280283 | 47/97 (48%) |
| ATP-grasp_4 | 248..452 | CDD:302634 | 104/203 (51%) | ||
| GSK-3_bind | 427..>543 | CDD:283100 | 46/154 (30%) | ||
| SYN3 | NP_001356836.1 | Synapsin_N | 1..29 | CDD:313741 | 10/33 (30%) |
| A | 1..28 | 8/30 (27%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 19..56 | 9/38 (24%) | |||
| B, linker | 28..90 | 18/72 (25%) | |||
| C, actin-binding and synaptic-vesicle binding | 91..399 | 154/347 (44%) | |||
| Synapsin | 93..190 | CDD:307960 | 47/96 (49%) | ||
| CPSase_L_D2 | 193..395 | CDD:354326 | 105/205 (51%) | ||
| PRK07764 | <394..536 | CDD:236090 | 36/150 (24%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 395..567 | 46/183 (25%) | |||
| J, Pro-rich linker | 400..531 | 35/137 (26%) | |||
| E | 532..580 | 18/50 (36%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 229 | 1.000 | Domainoid score | I2472 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3895 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H68320 | |
| Inparanoid | 1 | 1.050 | 375 | 1.000 | Inparanoid score | I2108 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S4740 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0001672 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41936 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104000 | |
| Panther | 1 | 1.100 | - | - | O | PTHR10841 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3309 |
| SonicParanoid | 1 | 1.000 | - | - | X1069 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.800 | |||||